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SUBMITTING THE MANUSCRIPT

Seminars in Arthritis and Rheumatism publishes articles that review basic science and clinical subjects related to the musculoskeletal system. Extended reviews, integrated analyses, and meta-analyses are encouraged. Manuscripts must be submitted through the Seminars in Arthritis and Rheumatism online submission and review Web site (http://ees.elsevier.com/sar/ ). Authors are requested to submit the text, tables, and artwork in electronic form (not as a PDF) to this address. Authors may send queries concerning the submission process, manuscript status, or journal procedures to the Editorial Office. Once the submission files are uploaded the system automatically generates electronic (PDF) proof, which is then used for reviewing. All correspondence, including the Editor's decision and request for revisions, will be by e-mail.

In an accompanying letter, authors should state that the manuscript, or parts of it, have not been and will not be submitted elsewhere for publication and that written permission as been obtained from all persons named in the acknowledgment. A separate statement will need to be signed referable to validity of authorship, financial disclosure and the acknowledgment. Verification of participation of those in the acknowledgment may be requested by the editorial office.

Authors are highly encouraged to include a list of three or more potential reviewers for their manuscript, with complete contact information.

The order of entry is as follows: Article title, selection of article type, Entering authors with their degree and affiliation, entering a structured abstract, entering at least 4 keywords, selecting document classifications (this helps in selecting reviewers), entering comments (this includes the cover letter and suggested reviewers), and attach files. The attached files should include the following: Title page, manuscript, table(s), figure (s), response to reviews (revised manuscripts only), and author disclosure (the latter may be sent by mail or FAX). Files should be labeled with appropriate and descriptive file names (e.g., SmithText.doc, Fig1, Table3.doc). Upload text, tables and graphics as separate files. Do not import figures or tables into the text document and do not upload your text as a PDF.

Authors who are unable to provide an electronic version or have other circumstances that prevent online submission must contact the Editorial Office at the address below prior to submission to discuss alternate options.

Roy D. Altman, M. D.
Editor, Seminars in Arthritis and Rheumatism
9854 West Bald Mountain Court
Agua Dulce, CA 91390
Telephone: +1-661-268-7328; FAX: +1-661-268-7658
E-mail: journals@royaltman.com

Authors submitting a manuscript do so with the understanding that if it is accepted for publication, copyright in the article, including the right to reproduce the article to all forms and media, shall be assigned exclusively to the Publisher. The Publisher will not refuse any reasonable request by the author for permission to reproduce any of his or her contributions to the journal.

Seminars in Arthritis and Rheumatism does publish Editorials, short manuscripts and letters to the editor. If submitting a case report, the case should exemplify and be a part of an extensive literature review of a specific rheumatic disease subject.

In addition to regular submissions, Seminars in Arthritis and Rheumatism will also consider publishing symposia that address special subjects or new developments in rheumatic disease as supplements to the regular issues. Organizers of symposia are encouraged to contact the editor as early as possible, and should provide a draft of the program. All manuscripts submitted to Seminars in Arthritis and Rheumatism must undergo review.

Copies of closely related papers or manuscripts that have been submitted or published elsewhere should accompany the submitted manuscript. Authors are responsible for providing a manuscript written in clear English. Delay, or even rejection, may result when papers are poorly written and in need of extensive editing. Authors whose primary language is not English are strongly encouraged to have their manuscript reviewed by an individual or organization competent in medical scientific English, where English is the primary language.

Letters to the Editor should limit content to commentaries on articles previously published by Seminars in Arthritis and Rheumatism. Letters should be double space and a maximum of 2 pages.

MANUSCRIPT FORMAT

Manuscript format should comply with the International Committee of Medical Journal Editors' "Uniform requirements for Manuscripts Submitted to Biomedical Journals" (N Engl J Med 1997:336:309-15) except where otherwise specifically indicated herein.

In all matters of style, please consult the Manual of Style (ed 8) published by the American Medical Association. Number each page sequentially, including the abstract, text, references, figure legends and tables starting with the title page as the first page.

The title page should contain (1) title of the contribution; (2) first name, middle initial, and last name of each author, with highest academic degree(s) (3) title and affiliated institution of each of the authors; (4) department(s) and institution(s) to which the work should be attributed (5) source(s) of support in the form of grants, equipment, or drugs; (6) disclaimers, such as conflicts of interest; (7) name, address, telephone number, FAX and e-mail of the corresponding author; (8) name and address for reprint requests. This information will be published with the manuscript unless requested otherwise.

All manuscripts require an ABSTRACT of fewer than 250 words that shall be structured as per the guidelines published in the Journal of the American Medical Association (JAMA) 2004;291:125-9. In this regard, the ABSTRACT should be placed into sections, at least including the following: (1) Objectives; (2) Methods -- if clinical to include setting, selection of patients, details on the intervention, outcome measures, etc.; if a literature review is included, details on the search methodology, if laboratory research to include details on methods; (3) Results; (4) Conclusions. As per JAMA, these guidelines apply to all manuscripts, including reviews.

It is requested that classification criteria be reported on patients, where relevant, by a brief description of the clinical features of patients, and by reference to the criteria used.

Begin each additional section of the manuscript with the appropriate title: INTRODUCTION, METHODS, RESULTS, DISCUSSION, ACKNOWLEDGEMENTS, REFERENCES, EACH INDIVIDUAL TABLE. FIGURE LEGENDS may be listed sequentially on the same page.

While authors should avoid unfamiliar abbreviations, a limited number of clearly defined abbreviations may be used. List the full word on its first appearance followed by the abbreviation in parenthesis. Once identified, the abbreviation should be used consistently in the text. If many abbreviations are used in the text, a glossary of abbreviations should be appended. Authors are encouraged to review the list of approved abbreviations.

Additional points: insert an extra blank line at the end of headings and paragraphs; type text without end of line hyphenation, except for compound words; be consistent with punctuation and only insert a single space between words and after punctuation.

TABLES AND FIGURES

Tables and figures should be cited in the text in order of appearance using Arabic numbers. Each table should be numbered and titled. A legend must accompany each illustration. The contributor must bear the costs connected with printing color illustrations.

Figures, especially charts, graphs and line drawings, are generally reduced in size for publication. All numbers, letters and symbols should be large enough that when reduced they will remain legible. Arrows should be added to radiographs, histology and other illustrations for clarity. Right and left sides should be labeled. Figures not properly prepared or of insufficient quality for publication will be returned to the contributor for revision. The best figures for publication are from electronic sources. However, power point and JPG files often are not of sufficient detail for print publications.

REFERENCES

References should be typed double-spaced and listed in numerical sequence as they are cited in the text. Names of the first six authors should be provided. For seven or more authors, list the first six followed by "et al". The reference style is based on the 'Uniform Requirements for Manuscripts Submitted to Biomedical Journals' (Ann Intern Med 1997;126:36-47). Both journal and book references should contain inclusive page numbers.

Personal communications and unpublished data should be cited in parentheses in the text, and not included in the numbered references listed at the end of the article. Such citations from someone other than the authors can only be published if a signed letter of permission is provided.

Reference to abstracts should be included only when essential, and then only if the abstract is from a readily accessible periodical. Such references must contain the word (Abstract) after the volume number of the journal.

References in the text should be at the end of the relevant sentence, given as numbers in brackets, parenthesis, or superscript, placed in line with the text and numbered in order of appearance.

EXAMPLES OF REFERENCES

Journal Articles

1. Standard Journal Articles (List all authors when six or less; when seven or more, list only the first six and et al.).

Ali M, Manolios N. Proteomics in rheumatology: a new direction for old diseases. Semin Arthritis Rheum 2005;35:67-76.

2. Corporate Author

FDA Document: Guidelines for Industry. The extent of population exposure to assess clinical safety: For drugs intended for long-term treatment of non life threatening conditions. ICH ELIA, March 2003; Federal Register March 1, 2003 (60FR11270).

Books

1. Personal Author(s)

Moskowitz RW, Howell DS, Altman RD, Buckwalter JA, and Goldberg VM. Osteoarthritis: Diagnosis and medical/surgical management, Third Edition, Philadelphia, W. B. Saunders 2001.

2. Corporate Author

Drug Information for the Health Care Professional. Volume 1 USP DI. Micromedex, Thomson Health Care, Quebecor World, Taunton, MA, XXII, 2002.

3. Editor, Compiler, Chairman as Author

Favus MJ, Ed. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, IV. An official publication of the American Society for Bone and Mineral Research. Lippincott Williams and Wilkins, Philadelphia 1999:1-502.

4. Chapter in Book

He X-S, Gershwin ME. Infection, autoimmunity and autoimmune liver disease. Infection and Autoimmunity, Shoenfeld and Rose Eds. Elsevier, Amsterdam. 2004:537-48.

Website

Uebersax J. A practical guide to local dependence in latent class models. http://ourworld.compuserve.com/homepages/jsuebersax/condep.htm accessed January 20, 2004.

PERMISSIONS

Authors are responsible for applying for permission for both print and electronic rights for all borrowed materials and are responsible for paying any fees related to the applications of these permissions.

PROOFREADING

Contributors are provided with electronic page proofs through the Gateway System and are asked to proofread them for typesetting errors. Important changes in data are allowed, but authors will be charged for excessive alterations in proof. Corrections must be entered within 48 hours.

REPRINTS

Reprints of articles will be furnished to contributors when ordered in advance of publication. An order form, showing cost of reprints, is sent with proofs. Individuals wishing to obtain reprints of an article that appeared in Seminars in Arthritis and Rheumatism can do so by contacting the author whose address appears on the first page of the article. MANUSCRIPT CHECKLIST Manuscript preparation--Text
• Double spacing of text and references
• Number pages

Title Page
• List all authors
• List academic titles of all authors
• Institution of origin
• Source of support
• Disclaimers
• Name of corresponding author with address, phone number, FAX number, e-mail address

Abstract
• 250 word abstract in style of the Journal of the American Medical Association

Body of Text
• References sequentially numbered and quoted in text
• Tables numbered sequentially and quoted in text
• Figures numbered sequentially and quoted in text
• Figure legends

References
• Vancouver style of reference with 6 authors prior to "et al."

Appended to Manuscript
• Statement signed by each author on authorship, responsibility, financial disclosure.