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Masthead
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IFC
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| Editorial |
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Sulfated oxysterols as candidates for the treatment of nonalcoholic fatty liver disease
05 March 2012
Nonalcoholic fatty liver disease (NAFLD) has emerged as a significant medical and socioeconomic burden. Its prevalence has been reported to be up to 45% of the general population in the USA and 6%–35...
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Stergios A. Polyzos,
Jannis Kountouras,
Christos S. Mantzoros
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755-758
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| Commentary |
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Vitamin D and insulin sensitivity: can gene association and pharmacogenetic studies of the vitamin D receptor provide clarity?
10 February 2012
Increasing evidence suggests that the 1,25-dihydroxyvitamin D (1,25[OH]2D)–vitamin D receptor (VDR) complex may play a role in a variety of human diseases beyond its established connection to skeletal...
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Anand Vaidya,
Jonathan S. Williams
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759-761
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| Review |
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Parathyromatosis: a rare yet problematic etiology of recurrent and persistent hyperparathyroidism
05 January 2012
Abstract: Recurrent or persistent hyperparathyroidism is an uncommon yet challenging clinical problem, and parathyromatosis is one of its very rare causes. In this minireview, we review causes of recu...
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Mirella P. Hage,
Ibrahim Salti,
Ghada El-Hajj Fuleihan
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762-775
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| Basic Science |
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Insulin resistance occurs in parallel with sensory neuropathy in streptozotocin-induced diabetes in rats: differential response to early vs late insulin supplementation
09 December 2011
Abstract: We investigated whether progressive sensory neuropathy was accompanied by changes in whole-body insulin sensitivity (WBIS) in rats made diabetic by streptozotocin (STZ). The effects of early...
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Zoltán Szilvássy,
Joseph Németh,
Péter Kovács,
György Paragh,
Réka Sári,
László Vígh,
Barna Peitl
et al.
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776-786
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The effect of ziprasidone on body weight and energy expenditure in female rats
30 December 2011
Abstract: Ziprasidone, a novel antipsychotic agent with a unique receptor-binding profile, has been reported to have lower propensity for weight gain compared with other atypical antipsychotics. Here,...
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Subin Park,
Min-Seon Kim,
Churl Namkoong,
Min-Hyeon Park,
Jin Pyo Hong
et al.
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787-793
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Administration of hydrogen-saturated saline decreases plasma low-density lipoprotein cholesterol levels and improves high-density lipoprotein function in high-fat diet–fed hamsters
08 December 2011
Abstract: Hydrogen (dihydrogen; H2) has an antiatherosclerotic effect in apolipoprotein (apo) E knockout mice. The goals of this study were to further characterize the effects of H2 on the content, co...
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Chuanlong Zong,
Guohua Song,
Shutong Yao,
Luqin Li,
Yang Yu,
Lei Feng,
Shoudong Guo,
Tian Luo,
Shucun Qin
et al.
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794-800
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Fatty acid profile of skeletal muscle phospholipid is altered in mdx mice and is predictive of disease markers
30 December 2011
Abstract: The mdx mouse is a model for Duchenne muscular dystrophy. The fatty acid (FA) composition in dystrophic muscle could potentially impact the disease severity. We tested FA profiles in skeleta...
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Marc A. Tuazon,
Gregory C. Henderson
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801-811
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Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats
30 December 2011
Abstract: Long-term metabolic effects induced by early nutritional changes are suspected to differ between males and females, but few studies have analyzed both sexes simultaneously. We analyzed the c...
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Esther Fuente-Martín,
Miriam Granado,
Cristina García-Cáceres,
Miguel A. Sanchez-Garrido,
Laura M. Frago,
Manuel Tena-Sempere,
Jesús Argente,
Julie A. Chowen
et al.
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812-822
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Antisense reduction of 11β-hydroxysteroid dehydrogenase type 1 enhances energy expenditure and insulin sensitivity independent of food intake in C57BL/6J mice on a Western-type diet
30 December 2011
Abstract: We recently reported that inhibition of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) by antisense oligonucleotide (ASO) improved hepatic lipid metabolism independent of food intake. In that...
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Guoping Li,
Antonio Hernandez-Ono,
Rosanne M. Crooke,
Mark J. Graham,
Henry N. Ginsberg
et al.
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823-835
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Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein–1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease
09 January 2012
Abstract: Cytosolic sulfotransferase (SULT2B1b) catalyzes oxysterol sulfation. 5-Cholesten-3β-25-diol-3-sulfate (25HC3S), one product of this reaction, decreases intracellular lipids in vitro by suppr...
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Qianming Bai,
Xin Zhang,
Leyuan Xu,
Genta Kakiyama,
Douglas Heuman,
Arun Sanyal,
William M. Pandak,
Lianhua Yin,
Wen Xie,
Shunlin Ren
et al.
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836-845
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| Meta-analysis |
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Methylenetetrahydrofolate reductase C677T gene polymorphism and coronary artery disease in a Chinese Han population: a meta-analysis
07 December 2011
Abstract: Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism has been suggested to be associated with increased coronary artery disease (CAD) risk. To explore the relationship between...
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Yan-yan Li
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846-852
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| Clinical Science |
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Association between serum fibroblast growth factor 21 and diabetic nephropathy
05 December 2011
Abstract: Fibroblast growth factor 21 (FGF-21) is a new metabolic regulator with beneficial effects on lipid and glucose metabolism in animal models of diabetes mellitus. The aim of this study was to ...
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Wei-Xia Jian,
Wen-Hui Peng,
Jie Jin,
Xue-Ru Chen,
Wen-Jun Fang,
Wei-Xing Wang,
Li Qin,
Yan Dong,
Qing Su
et al.
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853-859
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Effects of resistance exercise and obesity level on ghrelin and cortisol in men
07 December 2011
Abstract: Resistance exercise (RE) is increasingly recommended by health organizations as a weight management tool. The purpose of this study was to examine the effects of an acute high-volume, whole-...
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Gwendolyn A. Thomas,
William J. Kraemer,
Brett A. Comstock,
Courtenay Dunn-Lewis,
Jeff S. Volek,
Craig R. Denegar,
Carl M. Maresh
et al.
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860-868
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Physical activity is independently associated with multiple measures of arterial stiffness in adolescents and young adults
08 December 2011
Abstract: Physical activity (PA) is associated with decreased levels of arterial stiffness in adults, but the relationship between PA and multiple measures of arterial stiffness in adolescents and you...
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Nicholas M. Edwards,
Stephen R. Daniels,
Randall P. Claytor,
Philip R. Khoury,
Lawrence M. Dolan,
Thomas R. Kimball,
Elaine M. Urbina
et al.
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869-872
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Less fat reduction per unit weight loss in type 2 diabetic compared with nondiabetic obese individuals completing a very-low-calorie diet program
07 December 2011
Abstract: The objective was to compare weight loss and change in body composition in obese subjects with and without type 2 diabetes mellitus during a very-low-calorie diet (VLCD) program. Seventy wei...
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Scott T. Baker,
George Jerums,
Luke A. Prendergast,
Sianna Panagiotopoulos,
Boyd J. Strauss,
Joseph Proietto
et al.
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873-882
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A fruit and dairy dietary pattern is associated with a reduced risk of metabolic syndrome
30 December 2011
Abstract: This study examines the relationship between adherence to different dietary patterns and the presence of metabolic syndrome and its components among Korean adults. The sample consisted of 40...
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Soyoung Hong,
YoonJu Song,
Kye Heui Lee,
Hong Soo Lee,
Myoungsook Lee,
Sun Ha Jee,
Hyojee Joung
et al.
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883-890
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The ACE insertion/deletion polymorphism and its association with metabolic syndrome
30 December 2011
Abstract: The angiotensin-1–converting enzyme (ACE) gene has been suggested to be involved in the development of metabolic syndrome (MetS). However, results have been inconsistent. In this study, a me...
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Bo Xi,
Rikje Ruiter,
Jie Chen,
Haiyan Pan,
Ying Wang,
Jie Mi
et al.
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891-897
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Erratum
09 March 2012
In the article “Stronger associations of sagittal abdominal diameter with atherogenic lipoprotein subfractions than waist circumference in middle-aged US white and Japanese men” by Nakata et al (Metab...
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e5
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Erratum
09 March 2012
In the article “Higher liver fat content among Japanese in Japan compared with non- Hispanic whites in the US” by Azuma et al (Metabolism 2009; 58: 1200–7; doi:10.1016/j.metabol.2009.03.021), the foll...
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e7
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Table of Contents
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A1-A2
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Editorial Board
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A3
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