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Article Title |
Author(s) |
Type (Status) |
Available Online |
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The metabolic syndrome and coronary artery disease: A structural equation modeling approach suggestive of a common underlying pathophysiology
DOI: 10.1016/j.metabol.2012.04.010
Abstract: Objective: The purpose of this research was to utilize a structural equation modeling (SEM) approach to simultaneously examine the relationship among the Metabolic Syndrome (MetSyn) and coro...
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Jennifer E. Stevenson,
Bruce R. Wright,
Alan S. Boydstun
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Full-length article
(In Press Corrected Proof)
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24 May 2012 |
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Acetylation and deacetylation—novel factors in muscle wasting
DOI: 10.1016/j.metabol.2012.03.019
Abstract: We review recent evidence that acetylation and deacetylation of cellular proteins, including transcription factors and nuclear cofactors, may be involved in the regulation of muscle mass. Th...
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Nima Alamdari,
Zaira Aversa,
Estibaliz Castillero,
Per-Olof Hasselgren
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Review article
(In Press Corrected Proof)
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24 May 2012 |
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Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice
DOI: 10.1016/j.metabol.2012.04.015
Abstract: Objective: Emerging evidence suggests a link between innate immunity and development of type 2 diabetes mellitus (T2D); however, the molecular mechanisms linking them are not fully understoo...
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Linda H. Wu,
C. Chris Huang,
Sree Adhikarakunnathu,
Lani R. San Mateo,
Karen E. Duffy,
Patricia Rafferty,
Peter Bugelski,
Holly Raymond,
Heather Deutsch,
Kristen Picha,
Christine K. Ward,
Lena Alexoupolou,
Richard A. Flavell,
M. Lamine Mbow,
Vedrana S. Susulic
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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MicroRNA regulation of lipid metabolism
DOI: 10.1016/j.metabol.2012.04.009
Abstract: MicroRNAs are structural components of an epigenetic mechanism of post-transcriptional regulation of messenger RNA translation. Recently, there is significant interest in the application of ...
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Elena Flowers,
Erika Sivarajan Froelicher,
Bradley E. Aouizerat
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Review article
(In Press Corrected Proof)
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21 May 2012 |
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Snail, a transcriptional regulator, represses adiponectin expression by directly binding to an E-box motif in the promoter
DOI: 10.1016/j.metabol.2012.04.014
Abstract: Objective: Adiponectin is a hormone that modulates many metabolic processes and is exclusively expressed in adipose tissue. However, complete understanding of the factors that regulate adipo...
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Young Mi Park,
Yong-ho Lee,
Soo Hyun Kim,
Eun Young Lee,
Kyung-Sup Kim,
Darren R. Williams,
Hyun Chul Lee
et al.
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Full-length article
(In Press Corrected Proof)
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18 May 2012 |
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The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats
DOI: 10.1016/j.metabol.2012.03.014
Abstract: The aim of the present study was to investigate the participation of the sympathetic nervous system (SNS) in the control of glycerol-3-P (G3P) generating pathways in white adipose tissue (WA...
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Danúbia Frasson,
Renata Polessi Boschini,
Valéria Ernestânia Chaves,
Maria Emília Soares Martins dos Santos,
Sílvia de Paula Gomes,
Rafael Rossi Valentim,
Maria Antonieta Rissato Garófalo,
Luiz Carlos Carvalho Navegantes,
Renato Hélios Migliorini,
Isis do Carmo Kettelhut
et al.
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Full-length article
(In Press Corrected Proof)
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17 May 2012 |
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Leptin in congenital or HIV-associated lipodystrophy and metabolic syndrome: A need for more mechanistic studies and large, randomized, placebo-controlled trials
DOI: 10.1016/j.metabol.2012.04.013
Lipodystrophy is a clinically heterogeneous group of disorders characterized by abnormal adipose tissue metabolism, which is almost always complicated by metabolic derangements. The abnormal adipose t...
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Joo-Pin Foo,
Christos S. Mantzoros
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Editorial
(In Press Corrected Proof)
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17 May 2012 |
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Sulfated oxysterol 25HC3S as a therapeutic target of non-alcoholic fatty liver disease
DOI: 10.1016/j.metabol.2012.04.011
In mammals, triglycerides are predominantly synthesized in the liver by de novo lipogenesis and in turn, exported in the form of very low density lipoprotein (VLDL) particles to adipose and other tiss...
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Ji-Young Cha,
Young-Bum Kim
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Editorial
(In Press Corrected Proof)
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16 May 2012 |
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Effects of an intensive behavioral weight loss intervention consisting of caloric restriction with or without physical activity on common carotid artery remodeling in severely obese adults
DOI: 10.1016/j.metabol.2012.04.012
Abstract: Objective: Obesity increases cardiovascular disease risk and adversely affects vascular structure and function. Few studies have evaluated the vascular effects of non-surgical weight reducti...
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Jennifer N. Cooper,
Mindy L. Columbus,
Kelly J. Shields,
Julius Asubonteng,
Michelle L. Meyer,
Kim Sutton-Tyrrell,
Bret H. Goodpaster,
James P. DeLany,
John M. Jakicic,
Emma Barinas-Mitchell
et al.
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Full-length article
(In Press Corrected Proof)
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11 May 2012 |
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Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice
DOI: 10.1016/j.metabol.2012.04.006
Abstract: Objective: The aim of this study was to investigate the effect of CAPE on the insulin signaling and inflammatory pathway in the liver of mice with high fat diet induced obesity. Material/Met...
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Rosângela Maria Neves Bezerra,
Lucimara Fernanda Veiga,
Aline Camila Caetano,
Pedro Luiz Rosalen,
Maria Esméria Corezola Amaral,
Adrianne Christine Palanch,
Severino Matias de Alencar
et al.
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Full-length article
(In Press Corrected Proof)
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10 May 2012 |
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Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats
DOI: 10.1016/j.metabol.2012.04.008
Abstract: Objective: In a previous study, it was found that a ginseng berry extract with a high content of the ginsenoside Re normalized blood glucose in ob/ob mice. The objective of this study was to...
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Dong-Ho Han,
Sang Hyun Kim,
Kazuhiko Higashida,
Su-Ryun Jung,
Kenneth S. Polonsky,
Samuel Klein,
John O. Holloszy
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Adipocytokine profiles in a putative novel postmenopausal polycystic ovary syndrome (PCOS) phenotype parallel those in premenopausal PCOS: the Rancho Bernardo Study
DOI: 10.1016/j.metabol.2012.02.001
Abstract: The objective was to investigate whether the associations between leptin, adiponectin, andadiposity reported in classic polycystic ovary syndrome (PCOS) are also observed in elderly women wi...
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Andrew J. Krentz,
Denise von Mühlen,
Elizabeth Barrett-Connor
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Oral β-blockade in relation to energy expenditure in clinically stable patients with liver cirrhosis: A double-blind randomized cross-over trial
DOI: 10.1016/j.metabol.2012.04.001
Abstract: Elevated resting energy expenditure (REE) is seen in liver cirrhosis and is associated with reduced transplant-free survival. Non-selective β-blockers reduce REE in acute hypermetabolic cond...
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Wai Gin Lee,
John L. McCall,
Edward J. Gane,
Rinki Murphy,
Lindsay D. Plank
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Insulin and contraction-induced movement of fatty acid transport proteins to skeletal muscle transverse-tubules is distinctly different than to the sarcolemma
DOI: 10.1016/j.metabol.2012.04.002
Abstract: Fatty acid (FA) transport proteins are known to exist on the sarcolemma of skeletal muscle. However, it is unknown whether the t-tubules, which comprise ~60% of the cell surface, also harbor...
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Leslie E. Stefanyk,
Arend Bonen,
David J. Dyck
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Short communication
(In Press Corrected Proof)
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07 May 2012 |
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Self-reported speed of eating and 7-year risk of type 2 diabetes mellitus in middle-aged Japanese men
DOI: 10.1016/j.metabol.2012.04.005
Abstract: Objective: This cohort study investigated the association between eating speed and the incidence of type 2 diabetes in middle-aged Japanese men. Materials/Methods: Participants were 2,050 ma...
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Masaru Sakurai,
Koshi Nakamura,
Katsuyuki Miura,
Toshinari Takamura,
Katsushi Yoshita,
Shin-ya Nagasawa,
Yuko Morikawa,
Masao Ishizaki,
Teruhiko Kido,
Yuchi Naruse,
Yasushi Suwazono,
Satoshi Sasaki,
Hideaki Nakagawa
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin
DOI: 10.1016/j.metabol.2012.03.015
Abstract: The G protein-coupled receptor 83 (GPR83) was recently demonstrated in warm sensitive neurons (WSN) of the hypothalamic preoptic area (POA) that participate in temperature homeostasis. Thus,...
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Jeffrey S. Dubins,
Manuel Sanchez-Alavez,
Victor Zhukov,
Alejandro Sanchez-Gonzalez,
Gianluca Moroncini,
Santos Carvajal-Gonzalez,
John R. Hadcock,
Tamas Bartfai,
Bruno Conti
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Abnormal expression and function of Dectin-1 receptor in type 2 diabetes mellitus patients with poor glycemic control (HbA1c > 8%)
DOI: 10.1016/j.metabol.2012.03.020
Abstract: Dectin-1 is a key innate receptor involved in various cellular responses and may have a direct role in chronic inflammatory conditions such as type 2 diabetes mellitus. The aim of this work ...
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Nancy Cortez-Espinosa,
Mariana H. García-Hernández,
Elizabeth Reynaga-Hernández,
J. Diego Cortés-García,
Nancy E. Corral-Fernández,
J. Guillermo Rodríguez-Rivera,
Anamaría Bravo-Ramírez,
Roberto González-Amaro,
Diana P. Portales-Pérez
et al.
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Full-length article
(In Press Corrected Proof)
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04 May 2012 |
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GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases
DOI: 10.1016/j.metabol.2012.03.002
Abstract: Accumulating evidence has implicated that GLP-1 may have a beneficial effect on cardiovascular and renal diseases but the mechanism is not fully understood. Here we show that GLP-1 analog, l...
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Hari Hendarto,
Toyoshi Inoguchi,
Yasutaka Maeda,
Noriko Ikeda,
Jing Zheng,
Ryoko Takei,
Hisashi Yokomizo,
Eiichi Hirata,
Noriyuki Sonoda,
Ryoichi Takayanagi
et al.
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Full-length article
(In Press Corrected Proof)
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03 May 2012 |
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VEGF and angiopoietins in diabetic glomerulopathy: How far for a new treatment?
DOI: 10.1016/j.metabol.2012.04.004
Abstract: Diabetic nephropathy (DN) is the major cause of end-stage renal disease in Western countries and its prevalence continues to increase (United States Renal Data System 2010, http://www.usrds....
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Alessandra Dei Cas,
Luigi Gnudi
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Review article
(In Press Corrected Proof)
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03 May 2012 |
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Altered baroreflex and autonomic modulation in monosodium glutamate-induced hyperadipose rats
DOI: 10.1016/j.metabol.2012.03.005
Abstract: We aimed to examine the cardiovascular function by tonic and baroreflex alterations in obese rats induced by monosodium glutamate (MSG). Neonatal male Wistar rats were injected with MSG (4 m...
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Marlusa Karlen-Amarante,
Natália Veronez da Cunha,
Ozahyr de Andrade,
Hugo Celso Dutra de Souza,
Marli Cardoso Martins-Pinge
et al.
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Full-length article
(In Press Corrected Proof)
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03 May 2012 |
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Adipose triglyceride lipase and hormone-sensitive lipase protein expression in subcutaneous adipose tissue is decreased after an isoenergetic low-fat high-complex carbohydrate diet in the metabolic syndrome
DOI: 10.1016/j.metabol.2012.03.017
Abstract: The objective was to determine the contribution of dietary fat quantity and composition to lipolysis and lipolytic gene expression in humans in relation to obesity, insulin resistance, and t...
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Anneke M.J. van Hees,
Johan W.E. Jocken,
Yvonne Essers,
Helen M. Roche,
Wim H.M. Saris,
Ellen E. Blaak
et al.
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Full-length article
(In Press Corrected Proof)
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02 May 2012 |
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Allelic variations in the vitamin D receptor gene, insulin secretion and parents' heights are independently associated with height in obese children and adolescents
DOI: 10.1016/j.metabol.2012.03.018
Abstract: Polymorphisms in the VDR gene were reported to be associated with variations in intrauterine and postnatal growth and with adult height, but also with other traits that are strongly correlat...
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Daniela A.F. Ferrarezi,
Naïma Bellili-Muñoz,
Christiane Nicolau,
Nadir Cheurfa,
Isabel C. Guazzelli,
Eliana Frazzatto,
Gilberto Velho,
Sandra M. Villares
et al.
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Full-length article
(In Press Corrected Proof)
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02 May 2012 |
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Leptin replacement therapy does not improve the abnormal lipid kinetics of hypoleptinemic patients with HIV-associated lipodystrophy syndrome
DOI: 10.1016/j.metabol.2012.03.013
Abstract: Patients with HIV-associated dyslipidemic lipodystrophy (HADL) have characteristic lipid kinetic defects: accelerated lipolysis, blunted fat oxidation and increased hepatic fatty acid reeste...
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Rajagopal V. Sekhar,
Farook Jahoor,
Dinakar Iyer,
Anuradha Guthikonda,
Jaya Paranilam,
Fareed Elhaj,
Ivonne Coraza,
Ashok Balasubramanyam
et al.
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Full-length article
(In Press Corrected Proof)
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30 April 2012 |
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Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet
DOI: 10.1016/j.metabol.2012.03.012
Abstract: A promising approach to ameliorate obesity and obesity-associated diseases is the identification of new sources of dietary ingredients. The present study investigated the hepatic regulation ...
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Bodil Bjørndal,
Rita Vik,
Trond Brattelid,
Natalya Filipchuk Vigerust,
Lena Burri,
Pavol Bohov,
Ottar Nygård,
Jon Skorve,
Rolf K. Berge
et al.
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Full-length article
(In Press Corrected Proof)
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27 April 2012 |
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Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: A pilot study
DOI: 10.1016/j.metabol.2012.03.016
Abstract: Evidence suggests that ginger consumption has anti-inflammatory, anti-hypertensive, glucose-sensitizing, and stimulatory effects on the gastrointestinal tract. This study assessed the effect...
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Muhammad S. Mansour,
Yu-Ming Ni,
Amy L. Roberts,
Michael Kelleman,
Arindam RoyChoudhury,
Marie-Pierre St-Onge
et al.
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Short communication
(In Press Corrected Proof)
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26 April 2012 |
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Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes
DOI: 10.1016/j.metabol.2012.03.011
Abstract: Branched-chain amino acids (BCAAs) improve disorders of albumin metabolism, quality of life, subjective symptoms, and prognosis in patients with chronic hepatitis. However, it remains unclea...
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Yumie Takeshita,
Toshinari Takamura,
Yuki Kita,
Hitoshi Ando,
Teruyuki Ueda,
Kenichiro Kato,
Hirofumi Misu,
Hajime Sunagozaka,
Yoshio Sakai,
Tatsuya Yamashita,
Eishiro Mizukoshi,
Masao Honda,
Shuichi Kaneko
et al.
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Full-length article
(In Press Corrected Proof)
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23 April 2012 |
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Retinol-binding protein 4, insulin resistance and pregnancy
DOI: 10.1016/j.metabol.2012.03.008
Sir, the recent publication on retinol-binding protein 4 (RBP4), insulin resistance (IR) and pregnancy is very interesting . Khovidhunkit et al concluded, “Serum RBP4 levels in pregnancy are not assoc...
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Viroj Wiwanitkit
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Correspondence
(In Press Corrected Proof)
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20 April 2012 |
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Atorvastatin and pitavastatin enhance lipoprotein lipase production in L6 skeletal muscle cells through activation of adenosine monophosphate-activated protein kinase
DOI: 10.1016/j.metabol.2012.03.010
Abstract: Pravastatin and atorvastatin increase the serum level of lipoprotein lipase (LPL) mass in vivo but do not increase LPL activity in 3T3-L1 preadipocytes in vitro. LPL is mainly produced by ad...
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Masahiro Ohira,
Kei Endo,
Atsuhito Saiki,
Yoh Miyashita,
Kensuke Terai,
Takeyoshi Murano,
Fusako Watanabe,
Ichiro Tatsuno,
Kohji Shirai
et al.
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Full-length article
(In Press Corrected Proof)
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20 April 2012 |
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Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in Chronic Obstructive Pulmonary Disease
DOI: 10.1016/j.metabol.2012.03.001
Abstract: Exercise is known to improve physical functioning and health status in Chronic Obstructive Pulmonary Disease (COPD). Recently, disturbances in protein turnover and amino acid kinetics have b...
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Mariëlle P.K.J. Engelen,
Erica P.A. Rutten,
Carmen L.N. De Castro,
Emiel F.M. Wouters,
Annemie M.W.J. Schols,
Nicolaas E.P. Deutz
et al.
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Full-length article
(In Press Corrected Proof)
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18 April 2012 |
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Purified fish oil eliminating linoleic and alpha linolenic acid meets essential fatty acid requirements in rats
DOI: 10.1016/j.metabol.2012.03.007
Abstract: This study examined whether purified fish oil (PFO) supplemented to an essential fatty acid deficient (EFAD) diet meets EFA needs in rats. The EFAD diet contained 10% hydrogenated coconut oi...
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Pei-Ra Ling,
Mark Puder,
Bruce R. Bistrian
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Full-length article
(In Press Corrected Proof)
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18 April 2012 |
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Determinants of ApoB, ApoA1, and the ApoB/ApoA1 ratio in healthy schoolgirls, prospectively studied from mean ages 10 to 19 years: the Cincinnati National Growth and Health Study
DOI: 10.1016/j.metabol.2012.02.014
Abstract: The objectives were to prospectively assess determinants of apolipoproteins B (ApoB), A1 (ApoA1), and the ApoB/ApoA1 ratio in 797 healthy black and white schoolgirls from mean ages 10 to 19....
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John A. Morrison,
Charles J. Glueck,
Stephen R. Daniels,
Paul S. Horn,
Ping Wang
et al.
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Full-length article
(In Press Corrected Proof)
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18 April 2012 |
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Estrogen mediation of hormone responses to exercise
DOI: 10.1016/j.metabol.2012.03.009
Abstract: The roles of estrogens extend from the regulation of reproduction to other functions involved in control of metabolism, fluid balance, as well as gastrointestinal, lung, and brain function, ...
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Robert R. Kraemer,
Michelle Francois,
V. Daniel Castracane
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Review article
(In Press Corrected Proof)
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18 April 2012 |
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Promoting only the consumption of healthy foods may be an alternative stategy for treating patients with the metabolic syndrome
DOI: 10.1016/j.metabol.2012.03.004
Abstract: Objective: To evaluate the effectiveness of two lifestyle, interventional approaches on metabolic abnormalities and eating habits of patients with metabolic syndrome. Materials/Methods: This...
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Evaggelia Fappa,
Mary Yannakoulia,
Yannis Skoumas,
Stella Valourdou,
Demosthenes B. Panagiotakos,
Christos Pitsavos,
Christodoulos Stefanadis
et al.
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Full-length article
(In Press Corrected Proof)
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16 April 2012 |
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Vascular effects of intravenous intralipid and dextrose infusions in obese subjects
DOI: 10.1016/j.metabol.2012.03.006
Abstract: Hyperglycemia and elevated free fatty acids (FFA) are implicated in the development of endothelial dysfunction. Infusion of soy-bean oil-based lipid emulsion (Intralipid®) increases FFA leve...
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Aidar R. Gosmanov,
Dawn D. Smiley,
Limin Peng,
Joselita Siquiera,
Gonzalo Robalino,
Christopher Newton,
Guillermo E. Umpierrez
et al.
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Full-length article
(In Press Corrected Proof)
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09 April 2012 |
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Changes of metabolic and inflammatory markers in HIV infection: glucose, lipids, serum Hs-CRP and myeloperoxidase
DOI: 10.1016/j.metabol.2012.03.003
Abstract: Objective: HIV infection is exacerbated through additional pro-atherogenic mechanisms related to the processes of immune activation, inflammation, coagulation, and the modification of lipopr...
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Danielle Cristyane Kalva Borato,
Gisele Chibinski Parabocz,
Sônia Regina Weber Ribas,
Carlos Augusto Kalva-Filho,
Luciana Maria Borba,
Carmen Antonia Sanches Ito,
Larissa Bail,
Fábio André dos Santos,
José Carlos Rebuglio Vellosa
et al.
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Full-length article
(In Press Corrected Proof)
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05 April 2012 |
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Adding sprints to continuous exercise at the intensity that maximises fat oxidation: Implications for acute energy balance and enjoyment
DOI: 10.1016/j.metabol.2012.02.009
Abstract: The objective was to examine the effect of adding sprints to continuous exercise at the intensity that maximises fat oxidation (Fatmax) on energy expenditure, substrate oxidation, enjoyment ...
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Nicole A. Crisp,
Paul A. Fournier,
Melissa K. Licari,
Rebecca Braham,
Kym J. Guelfi
et al.
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Full-length article
(In Press Corrected Proof)
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05 April 2012 |
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Over-nutrition and metabolic cardiomyopathy
DOI: 10.1016/j.metabol.2012.02.013
Abstract: Cardiovascular disease, which accounts for the highest morbidity and mortality in the United States, has several major risk factors, including aging and diabetes. Overweight and obesity, esp...
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Chirag H. Mandavia,
Lakshmi Pulakat,
Vincent DeMarco,
James R. Sowers
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Review article
(In Press Corrected Proof)
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01 April 2012 |
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CYP1B1 Asn453Ser polymorphism and colorectal cancer risk: a meta-analysis
DOI: 10.1016/j.metabol.2012.02.010
Abstract: Studies investigating the association between cytochrome P450 1B1 (CYP1B1) Asn453Ser (453 A/G, rs1800440) polymorphism and colorectal cancer (CRC) risk report conflicting results. The aim of...
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Qiang Mei,
Daijun Zhou,
Jialong Han,
Hai Lu,
Bo Tang
et al.
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Full-length article
(In Press Corrected Proof)
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30 March 2012 |
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A cross-over study of the acute effects of espresso coffee on glucose tolerance and insulin sensitivity in people with type 2 diabetes mellitus
DOI: 10.1016/j.metabol.2012.01.021
Abstract: The objective was to determine the effect of a single dose of espresso caffeinated coffee, decaffeinated coffee, or water on glucose tolerance and insulin sensitivity in people with type 2 d...
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Jeremy D. Krebs,
Amber Parry-Strong,
Mark Weatherall,
Richard W. Carroll,
Michelle Downie
et al.
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Full-length article
(In Press Corrected Proof)
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29 March 2012 |
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Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain–hypothalamic neural pathways in rats
DOI: 10.1016/j.metabol.2012.02.011
Abstract: The intestine plays important roles in the regulation of feeding behavior by sensing macronutrients. Intestinal fatty acids strongly suppress food intake, but little is known about whether i...
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Nobuya Ogawa,
Makoto Ito,
Hideki Yamaguchi,
Tetsuya Shiuchi,
Shiki Okamoto,
Korekiyo Wakitani,
Yasuhiko Minokoshi,
Masamitsu Nakazato
et al.
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Full-length article
(In Press Corrected Proof)
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27 March 2012 |
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Fatty acid flux and oxidation are increased by rimonabant in obese women
DOI: 10.1016/j.metabol.2012.02.012
Abstract: This study aimed to determine in obese women if endocannabinoid receptor antagonism has effects on fatty acid and triglyceride metabolism and insulin sensitivity which are independent from t...
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Katharine Backhouse,
Ivana Sarac,
Fariba Shojaee-Moradie,
Michael Stolinski,
M. Denise Robertson,
Gary S. Frost,
Jimmy D. Bell,
E. Louise Thomas,
John Wright,
David Russell-Jones,
A. Margot Umpleby
et al.
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Short communication
(In Press Corrected Proof)
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26 March 2012 |
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Polymorphisms of POR, SULT2A1 and HSD11B1 in children with premature adrenarche
DOI: 10.1016/j.metabol.2012.02.008
Abstract: Premature adrenarche (PA) refers to an earlier than normal increase in adrenocortical androgen production. The pathogenesis of PA remains largely unknown. We hypothesized that common polymor...
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Pauliina Utriainen,
Saila Laakso,
Jarmo Jääskeläinen,
Raimo Voutilainen
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Short communication
(In Press Corrected Proof)
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26 March 2012 |
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A randomized trial of copper supplementation effects on blood copper enzyme activities and parameters related to cardiovascular health
DOI: 10.1016/j.metabol.2012.02.002
Abstract: Marginal copper deficiency, which may affect cardiovascular disease risk, is proposed to occur in many adults in Western industrialized countries. The present study tested the hypothesis tha...
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Robert A. DiSilvestro,
Elizabeth L. Joseph,
Wenyi Zhang,
Adrienne E. Raimo,
Young Min Kim
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Race–ethnic differences in adipokine levels: the Study of Women's Health Across the Nation (SWAN)
DOI: 10.1016/j.metabol.2012.02.005
Abstract: Diffferences in adipose tissue secretory profile, as measured by adipokine levels, may play a role in race–ethnic disparities in cardiovascular disease (CVD). We examined race–ethnic differe...
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Unab I. Khan,
Dan Wang,
Maryfran R. Sowers,
Peter Mancuso,
Susan A. Everson-Rose,
Philipp E. Scherer,
Rachel P. Wildman
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Influence of obesity indices, metabolic parameters and age on cardiac autonomic function in abdominally obese men
DOI: 10.1016/j.metabol.2012.02.006
Abstract: Heart rate variability (HRV) is affected by age, hyperglycemia and accumulation of body fat. This study compares the predictive value of four measurements of adiposity/obesity on HRV and inv...
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Natalia Poliakova,
Jean-Pierre Després,
Jean Bergeron,
Natalie Alméras,
Angelo Tremblay,
Paul Poirier
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Elevated IgG levels against specific bacterial antigens in obese patients with diabetes and in mice with diet-induced obesity and glucose intolerance
DOI: 10.1016/j.metabol.2012.02.007
Abstract: High fat diets increase the risk for insulin resistance by promoting inflammation. The cause of inflammation is unclear, but germfree mouse studies have implicated commensal gut bacteria. We...
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Nadeem Mohammed,
Lihua Tang,
Anisa Jahangiri,
Willem de Villiers,
Erik Eckhardt
et al.
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Short communication
(In Press Corrected Proof)
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19 March 2012 |
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Metformin decreases plasma resistin concentrations in pediatric patients with impaired glucose tolerance: a placebo-controlled randomized clinical trial
DOI: 10.1016/j.metabol.2012.02.003
Abstract: The objective was to determine the effect of metformin on the concentrations of resistin and other markers of insulin resistance or inflammation (C-reactive protein, cytokines, body weight, ...
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Rita A. Gómez-Díaz,
Juan O. Talavera,
Elsy Canché Pool,
Francisco Vianney Ortiz-Navarrete,
Fortino Solórzano-Santos,
Rafael Mondragón-González,
Adan Valladares-Salgado,
Miguel Cruz,
Carlos A. Aguilar-Salinas,
Niels H. Wacher
et al.
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Full-length article
(In Press Corrected Proof)
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19 March 2012 |
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Lean mass and insulin resistance in women with polycystic ovary syndrome
DOI: 10.1016/j.metabol.2012.02.004
Abstract: Insulin resistance is common in women with polycystic ovary syndrome (PCOS). Muscle is the major tissue utilizing glucose while excess adipose tissue relates to insulin resistance. Thus, bod...
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Kevin B. Comerford,
Rogelio U. Almario,
Kyoungmi Kim,
Sidika E. Karakas
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Full-length article
(In Press Corrected Proof)
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19 March 2012 |
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Hypothyroidism: age-related influence on cardiovascular nitric oxide system in rats
DOI: 10.1016/j.metabol.2012.01.022
Abstract: This study investigates whether changes in nitric oxide (NO) production participate in the cardiovascular manifestations of hypothyroidism and whether these changes are age-related. Sprague–...
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Lorena I. Sarati,
Carla R. Martinez,
Nicolás Artés,
Noelia Arreche,
Juan J. López-Costa,
Ana M. Balaszczuk,
Andrea L. Fellet
et al.
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Full-length article
(In Press Corrected Proof)
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19 March 2012 |
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Carbohydrate supplementation increases intramyocellular lipid stores in elite runners
DOI: 10.1016/j.metabol.2012.01.013
Abstract: The objective was to determine the effects of carbohydrate (CHO) supplementation on exercise-induced hormone responses and post-training intramyocellular lipid stores (IMCL). Twenty-four eli...
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Maysa Sousa,
Herbert Gustavo Simões,
Cláudio Campi de Castro,
Maria Concepción García Otaduy,
Carlos Eduardo Negrão,
Rosa Maria Rodrigues Pereira,
Klavs Madsen,
Maria Elizabeth Rossi da Silva
et al.
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Full-length article
(In Press Corrected Proof)
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14 March 2012 |
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Association between hippocampal volume and serum adiponectin in patients with type 2 diabetes mellitus
DOI: 10.1016/j.metabol.2012.01.016
Abstract: Type 2 diabetes mellitus (DM) is associated with cognitive dysfunction and hippocampus volume. The aim of the present study was to test the hypothesis that the level of the adipocytokine adi...
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Takayuki Masaki,
Futoshi Anan,
Tsuyoshi Shimomura,
Minoru Fujiki,
Tetsunori Saikawa,
Hironobu Yoshimatsu
et al.
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Full-length article
(In Press Corrected Proof)
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12 March 2012 |
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The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer
DOI: 10.1016/j.metabol.2012.01.017
Abstract: Dietary fiber (DF) is deemed to be a key component in healthy eating. DF is not a static collection of undigestible plant materials that pass untouched or unencumbered through the gastrointe...
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Melissa M. Kaczmarczyk,
Michael J. Miller,
Gregory G. Freund
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Review article
(In Press Corrected Proof)
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09 March 2012 |
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Sex differences in the effect of high-fat diet feeding on rat white adipose tissue mitochondrial function and insulin sensitivity
DOI: 10.1016/j.metabol.2011.12.016
Abstract: Obesity-induced mitochondrial dysfunction in white adipose tissue (WAT) leads to a dysregulation of adipokine secretion, which is involved in insulin resistance development. Taking into acco...
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Emilia Amengual-Cladera,
Isabel Lladó,
Magdalena Gianotti,
Ana M. Proenza
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Fibroblast growth factor-21 protects human skeletal muscle myotubes from palmitate-induced insulin resistance by inhibiting stress kinase and NF-κB
DOI: 10.1016/j.metabol.2012.01.012
Abstract: We investigated the effects of fibroblast growth factor-21 (FGF-21) on palmitate-induced insulin resistance in skeletal muscle myotubes. First, to determine the effect of FGF-21 on palmitate...
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Min Suk Lee,
Sung-E Choi,
Eun Suk Ha,
So-Yeon An,
Tae Ho Kim,
Seung Jin Han,
Hae Jin Kim,
Dae Jung Kim,
Yup Kang,
Kwan-Woo Lee
et al.
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Full-length article
(In Press Corrected Proof)
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07 March 2012 |
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High tea and vegetable consumption is associated with low ADMA generation in older healthy subjects
DOI: 10.1016/j.metabol.2011.12.013
Abstract: Asymmetric dimethylarginine (ADMA) has been recognized as a marker of cardiovascular risk. We sought to investigate whether consumption of tea, coffee, fruit or vegetables is associated with...
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Tadeusz Goralczyk,
Joanna Tisonczyk,
Kamil Fijorek,
Anetta Undas
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Full-length article
(In Press Corrected Proof)
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05 March 2012 |
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Podocytes and the struggle against glucose toxicity: New targets for treatment?
DOI: 10.1016/j.metabol.2012.01.015
Podocytes have an important role in the maintenance of glomerular capillary architecture/function. Studies suggests that in glomerular diseases podocytes' damage often triggers a cascade of events tha...
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Luigi Gnudi
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Editorial
(In Press Corrected Proof)
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05 March 2012 |
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Increased action of pulsatile compared to non-pulsatile insulin delivery during a meal-like glucose exposure simulated by computerized infusion in healthy humans
DOI: 10.1016/j.metabol.2011.12.014
Abstract: It has previously been demonstrated that pulsatile insulin has a greater hypoglycemic effect than non-pulsatile insulin during euglycemic conditions. The aim of the present study was to exam...
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Claus B. Juhl,
Jacob Gjedsted,
Michael F. Nielsen,
Ole Schmitz
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Full-length article
(In Press Corrected Proof)
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05 March 2012 |
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Estrogen therapy attenuates adiposity markers in spontaneously hypertensive rats
DOI: 10.1016/j.metabol.2011.12.015
Abstract: Ovarian hormones modulate the metabolism of adipose cells and present a protective effect against hypertension. The aim of this study was to compare the effect of estradiol on adiposity mark...
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Eva das Graças Abeles,
Letícia Maria de Souza Cordeiro,
Almir de Sousa Martins,
Jorge Luiz Pesquero,
Adelina Martha dos Reis,
Silvia Passos Andrade,
Leida Maria Botion
et al.
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Full-length article
(In Press Corrected Proof)
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05 March 2012 |
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Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice
DOI: 10.1016/j.metabol.2012.01.018
Abstract: Adipose tissue macrophages are important mediators of inflammation and insulin resistance in obesity. IFN-γ is a central regulator of macrophage function. The role of IFN-γ in regulating sys...
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Robert W. O'Rourke,
Ashley E. White,
Monja D. Metcalf,
Brian R. Winters,
Brian S. Diggs,
Xinxia Zhu,
Daniel L. Marks
et al.
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Full-length article
(In Press Corrected Proof)
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05 March 2012 |
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Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level
DOI: 10.1016/j.metabol.2012.01.006
Abstract: Advanced glycation end products (AGEs) and their receptor (RAGE) axis play a role in diabetic nephropathy. Statins have been shown to ameliorate renal function and reduce proteinuria in pati...
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Yuji Ishibashi,
Sho-ichi Yamagishi,
Takanori Matsui,
Keisuke Ohta,
Ryuichiro Tanoue,
Masayoshi Takeuchi,
Seiji Ueda,
Kei-ichiro Nakamura,
Seiya Okuda
et al.
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Short communication
(In Press Corrected Proof)
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05 March 2012 |