Current Issue June 2012, Vol. 37, No. 6

Foreword to Current Issue

Foreword The measurement of biomarkers is an essential part of everyday clinical practice. It is a pivotal diagnostic step in the diagnosis of acute myocardial infarction. However, there are problems: (1) many other clinical situations are associated with elevated troponins; and (2) normal athletes.

Current Topic

Troponin— Past, Present, and Future Cardiac troponin is the analyte of choice for the diagnosis of cardiac injury. It is highly specific for the heart and much more sensitive than prior biomarkers. Because of this increased sensitivity, clinicians have had to struggle with elevations in novel clinical situations. We have developed new understandings about coronary artery disease but also have begun to appreciate that many other entities as well can result in cardiac injury. As assays have increased in sensitivity over time, this trend has, if anything, accelerated. This review attempts to put the past, the present, and the future into a clinical perspective that will help clinicians.

Last Month's Topic

Cervical Carotid Artery Stenosis: Latest Update on Diagnosis and Management Carotid atherosclerotic disease is implicated in 15% to 30% of all ischemic strokes. Carotid endarterectomy has been the standard treatment for carotid artery atherosclerosis, but carotid angioplasty and stenting have emerged as a less-invasive treatment alternative. In this article, we review the recent literature on the epidemiology, pathophysiology, investigations, and treatment for atherosclerotic carotid artery disease, focusing on the role of carotid endarterectomy and carotid angioplasty and stenting in the treatment of symptomatic and asymptomatic carotid lesions.

  • Imaging for Atrial Fibrillation
    January 2012 (Vol. 37 | No. 1 | Pages 7-33)

    Darryl P. Leong, Victoria Delgado, Jeroen J. Bax

  • Pericardial Diseases
    March 2012 (Vol. 37 | No. 3 | Pages 75-118)

    David M. Dudzinski, Gary S. Mak, Judy W. Hung

  • Table of Contents
    March 2012 (Vol. 37 | No. 3 | Pages 71-72)

  • Percutanenous Therapies for Mitral Regurgitation
    February 2012 (Vol. 37 | No. 2 | Pages 42-68)

    Alice Perlowski, Frederick St. Goar, Donald G. Glower, Ted Feldman

  • Table of Contents
    April 2012 (Vol. 37 | No. 4 | Pages 121-122)

Most Read lists are compiled every quarter.

Cover Image
Shahbudin H. Rahimtoola, MB, FRCP MACP, MACC, DSc. (Hon)

Journal Ranking

Impact Factor:
2010: 3.435
© Thomson Reuters Journal Citation Reports 2011

Publishing Information

Current Problems in Cardiology is published by Elsevier.

Access this journal onSciVerse ScienceDirect
Print or Share This Page

On the Cover

?

Detection of skeletal muscle proteins by the antibodies used in the cTnT assay. Western blot of SMD from patients with myopathies in lanes 1-4, normal human heart muscle in lane 5, and normal human soleus muscle in lane 6. Note molecular weight designations on the ordinate. The antibodies used in the standard cTnT assay (M7 and M11-7) and those used in the high-sensitivity assay (M7 and 5D8) all tag a protein at a molecular weight of about 39 kDa. This suggests strongly that the 2 antibodies in each of these assays would detect these proteins in blood, indicating that there is a good possibility that elevations in cTnT or the high sensitivity cardiac troponin T assay could occur because of diseased skeletal muscle.

Journal Access

Full-text articles are available from 2000 to the present; abstracts, references and PDFs are available from 1996 to the present. Access to tables of contents and abstracts is complimentary. Access to full text is limited to personal subscribers.

Activate Online Access

About Current Problems in Cardiology

For more than 30 years, Current Problems in Cardiology has provided focused, comprehensive coverage of important clinical topics in cardiology. In most monthly issues, authors address a selected clinical problem or condition, including pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation. Other issues explore the clinical applications of a diagnostic modality or a particular category of drugs. Critical commentary from the distinguished editorial board accompanies each monograph, providing readers with additional insights. An extensive bibliography in each issue saves hours of library research.