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Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.
Malathi Hari, Frank Loganzo, Tami Annable, Xingzhi Tan, Sylvia Musto, Daniel B Morilla, James H Nettles, James P Snyder, Lee M Greenberger
Mol Cancer Ther
Feb 2006 (Vol. 5, Issue 2, Pages 270-8)
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	A one-step synthesis of a deuterated paclitaxel analogue: 10-deacetoxy-(10alpha-2H)paclitaxel. D Dutta, H Hadd, D G Vander Velde, G I Georg Bioorg Med Chem Lett December 1999 (Vol. 9, Issue 23, Pages 3277-8) MEDLINE \| Related Records
	Association of acquired Pelger-Huet anomaly with taxoid therapy. S K Juneja, J P Matthews, R Luzinat, Y Fan, M Michael, D Rischin, M J Millward, G C Toner Br J Haematol April 1996 (Vol. 93, Issue 1, Pages 139-41) MEDLINE \| Related Records
	Treatment of patients resistant to paclitaxel therapy. V Valero Anticancer Drugs August 1996 (Vol. 7 Suppl 2, Pages 17-9) MEDLINE \| Related Records
	Docetaxel. M Leahy, A Howell Br J Hosp Med February 1997 (Vol. 57, Issue 4, Pages 141-4) MEDLINE \| Related Records
	Determination of a new polymer-bound paclitaxel derivative (PNU 166945), free paclitaxel and 7-epipaclitaxel in dog plasma and urine by reversed-phase high-performance liquid chromatography with UV detection. D Fraier, V Cenacchi, E Frigerio J Chromatogr A February 1998 (Vol. 797, Issue 1-2, Pages 295-303) MEDLINE \| Related Records
	Management of toxicities associated with the administration of taxanes. Maurie Markman Expert Opin Drug Saf March 2003 (Vol. 2, Issue 2, Pages 141-6) MEDLINE \| Related Records
	The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. R E Ketchum, D M Gibson, R B Croteau, M L Shuler Biotechnol Bioeng January 1999 (Vol. 62, Issue 1, Pages 97-105) MEDLINE \| Related Records
	Paclitaxel and docetaxel in breast and ovarian cancer. Drug Ther Bull June 1997 (Vol. 35, Issue 6, Pages 43-6) MEDLINE \| Related Records
	The taxoids: paclitaxel (Taxol) and docetaxel (Taxotere). R Pazdur, A P Kudelka, J J Kavanagh, P R Cohen, M N Raber Cancer Treat Rev October 1993 (Vol. 19, Issue 4, Pages 351-86) MEDLINE \| Related Records
	The taxoids: paclitaxel and docetaxel. K Gelmon Lancet November 1994 (Vol. 344, Issue 8932, Pages 1267-72) MEDLINE \| Related Records
	Chemistry and chemical biology of taxane anticancer agents. M L Miller, I Ojima Chem Rec January 2001 (Vol. 1, Issue 3, Pages 195-211) MEDLINE \| Related Records
	Biotransformation of taxoids by human cytochromes P450: structure-activity relationship. B Monsarrat, I Royer, M Wright, T Cresteil Bull Cancer February 1997 (Vol. 84, Issue 2, Pages 125-33) MEDLINE \| Related Records
	Taxoids: cancer-fighting compounds from nature. David G I Kingston, David J Newman Curr Opin Drug Discov Devel March 2007 (Vol. 10, Issue 2, Pages 130-44) MEDLINE \| Related Records
	[Provision of taxoids in 1996: inequality of care] I A Eland, R Otter, R Krommendijk, B H Stricker Ned Tijdschr Geneeskd March 1998 (Vol. 142, Issue 10, Pages 518-21) MEDLINE \| Related Records
	Biological activity and chemistry of taxoids from the Japanese yew, Taxus cuspidata. Hideyuki Shigemori, Jun'ichi Kobayashi J Nat Prod February 2004 (Vol. 67, Issue 2, Pages 245-56) MEDLINE \| Related Records
	Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously. Eric J Gapud, Ruoli Bai, Arun K Ghosh, Ernest Hamel Mol Pharmacol July 2004 (Vol. 66, Issue 1, Pages 113-21) MEDLINE \| Related Records
	Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cells. E A Oldham, C Li, S Ke, S Wallace, P Huang Int J Oncol January 2000 (Vol. 16, Issue 1, Pages 125-32) MEDLINE \| Related Records
	Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: a phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer. A D Seidman, D Hochhauser, M Gollub, B Edelman, T J Yao, C A Hudis, P Francis, D Fennelly, T A Gilewski, M E Moynahan, V Currie, J Baselga, W Tong, M O'Donaghue, R Salvaggio, L Auguste, D Spriggs, L Norton J Clin Oncol June 1996 (Vol. 14, Issue 6, Pages 1877-84) MEDLINE \| Related Records
	Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate. C Li, D F Yu, R A Newman, F Cabral, L C Stephens, N Hunter, L Milas, S Wallace Cancer Res June 1998 (Vol. 58, Issue 11, Pages 2404-9) MEDLINE \| Related Records
	Breath alcohol concentrations in Japanese outpatients following paclitaxel and docetaxel infusion. H Komagata, S Yoneda, H Sakai, K Isobe, T Shirai, M Fujimura, T Tabei, K Inoue Int J Clin Pharmacol Res January 2005 (Vol. 25, Issue 4, Pages 195-202) MEDLINE \| Related Records

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