Current Issue February 2012, Vol. 129, No. 2

Featured Article of the Week

Prostaglandin D2–induced eotaxin-3 through peroxisome proliferator–activated receptor γ from sebocytes involves perifollicular eosinophil infiltration In this issue Nakahigashi et al (p 536) provide evidence that prostaglandin D (PGD) 2 has an indirect effect on eosinophil infiltration by inducing eotaxin-3, a chemoattractant for eosinophils, from sebocytes. This is the first report that PGD2 induces eotaxin-3 in sebocytes (see Figure).

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Supplement Issue

Gene-environment interaction in chronic disease: A European Science Foundation Forward Look

Which disease is cured by Lactobacillus?
10 February 2012
Michael Goldberg, Yitzhak Katz
We read with interest the article by Canani et al that evaluates the effect of Lactobacillus GG on tolerance acquisition in infants with cow's milk allergy (CMA). Their method of selection and classif...
Food protein–induced enterocolitis syndrome in an exclusively breast-fed infant—an uncommon entity
10 February 2012
John Tan, Dianne Campbell, Sam Mehr
We read with interest the report by Monti et al of the only published case of food protein–induced enterocolitis syndrome (FPIES) triggered by cow's milk protein in breast milk. We can also report a c...
Reply
10 February 2012
Giovanna Monti, Emanuele Castagno, Stefania Alfonsina Liguori, Maria Maddalena Lupica, Valentina Tarasco, Serena Viola
We read with great interest the comments by Tan et al regarding our case report of an exclusively breast-fed infant with food protein–induced enterocolitis syndrome (FPIES) to cow's milk proteins.
The developmental trajectory of pediatric asthma in 3- to-10-year-olds
10 February 2012
Pingsheng Wu, Kecia N. Carroll, Tebeb Gebretsadik, William D. Dupont, Edward F. Mitchel, Tina V. Hartert
Longitudinal studies have suggested that early childhood asthma follows different temporal trajectories. Children with early childhood recurrent wheezing frequently have “symptom- or disease-free” per...
A fascinating look at the world with a new microscope
10 February 2012
Erika von Mutius
In the mid-17th century in Delft, Antony Leeuwenhoek was the first to invent the microscope. He was enormously skilled in making lenses and mounted them on frames that would eventually become the firs...

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Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel
December 2010 (Vol. 126 | No. 6 | Pages S1-S58)
NIAID-Sponsored Expert Panel
Eosinophilic esophagitis: Updated consensus recommendations for children and adults
July 2011 (Vol. 128 | No. 1 | Pages 3-20.e6)
Chris A. Liacouras, Glenn T. Furuta, Ikuo Hirano, Dan Atkins, Stephen E. Attwood, Peter A. Bonis, A. Wesley Burks, Mirna Chehade, Margaret H. Collins, Evan S. Dellon, Ranjan Dohil, Gary W. Falk, Nirmala Gonsalves, Sandeep K. Gupta, David A. Katzka, Alfredo J. Lucendo, Jonathan E. Markowitz, Richard J. Noel, Robert D. Odze, Philip E. Putnam, Joel E. Richter, Yvonne Romero, Eduardo Ruchelli, Hugh A. Sampson, Alain Schoepfer, Nicholas J. Shaheen, Scott H. Sicherer, Stuart Spechler, Jonathan M. Spergel, Alex Straumann, Barry K. Wershil, Marc E. Rothenberg, Seema S. Aceves
Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision
September 2010 (Vol. 126 | No. 3 | Pages 466-476)
Jan L. Brożek, Jean Bousquet, Carlos E. Baena-Cagnani, Sergio Bonini, G. Walter Canonica, Thomas B. Casale, Roy Gerth van Wijk, Ken Ohta, Torsten Zuberbier, Holger J. Schünemann
Asthma diagnosis and treatment: Filling in the information gaps
October 2011 (Vol. 128 | No. 4 | Pages 740-750)
William W. Busse
The Asthma Predictive Index: A very useful tool for predicting asthma in young children
August 2010 (Vol. 126 | No. 2 | Pages 212-216)
Jose A. Castro-Rodriguez

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About the Journal

An official publication of the American Academy of Allergy, Asthma, and Immunology, The Journal of Allergy and Clinical Immunology brings timely clinical papers, instructive case reports, and detailed examinations of state-of-the-art equipment and techniques to clinical allergists, immunologists, dermatologists, internists, and other physicians concerned with clinical manifestations of allergies in their practice. More

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Audio

5 audios:

Rhinitis and sinusitis (October 2011): Associate Editor Pedro Avila discusses recent JACI articles on rhinitis and sinusitis, with insights from the articles' authors.

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Asthma highlights (August 2011): Deputy Editor Stanley Szefler discusses recent JACI asthma review articles, with insights from the articles' authors. (14m 34s).

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Gut microbiota, nutrition, and allergic disease (May 2011): Diane Gold reviews some of the highlights of the JACI's May 2011 issue.

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Food allergy (March 2011): Associate Editor Scott Sicherer reviews some of highlights of the JACI's March 2011 food allergy issue.

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Allergen immunotherapy (February 2011): AAAAI Executive Vice President Thomas Casale discusses some of the highlights of the JACI's recent issue on allergen immunotherapy. (7m 30s)

Allergy immunotherapy (February 2011): AAAAI Executive Vice President Thomas Casale discusses some of the highlights of the JACI's recent issue on allergen immunotherapy. (7m 30s)

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Asthma: Current Status and Future Directions

A mini-series of reviews, written by some of the leaders in the field, that discuss our current understanding of the "big questions" in asthma.

Press Release

Scientists Identify Strategies to Conquer Lifestyle and Genetic Factors Related to Chronic Diseases Recommendations Published in JACI Supplement

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The JACI is pleased to announce a new Shared Science program with Immunity. Click here to access the articles!

About AAAAI

The American Academy of Allergy, Asthma & Immunology is the largest professional medical organization in the United States devoted to the allergy/immunology specialty. The AAAAI represents asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic disease. The AAAAI is devoted to the advancement of the knowledge and practice of allergy, asthma and immunology for optimal patient care.

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