| Critical Review |
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Brain Stimulation in the Treatment of Chronic Neuropathic and Non-Cancerous Pain
09 April 2012
Abstract: Chronic neuropathic pain is one of the most prevalent and debilitating disorders. Conventional medical management, however, remains frustrating for both patients and clinicians owing to poor...
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Ela B. Plow,
Alvaro Pascual-Leone,
Andre Machado
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411-424
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| Original Reports |
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Associations Between Pro- and Anti-Inflammatory Cytokine Genes and Breast Pain in Women Prior to Breast Cancer Surgery
20 April 2012
Abstract: The purposes of this study were to determine the occurrence rate for preoperative breast pain; describe the characteristics of this pain; evaluate for differences in demographic and clinical...
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Birha McCann,
Christine Miaskowski,
Theresa Koetters,
Christina Baggott,
Claudia West,
Jon D. Levine,
Charles Elboim,
Gary Abrams,
Deborah Hamolsky,
Laura Dunn,
Hope Rugo,
Marylin Dodd,
Steven M. Paul,
John Neuhaus,
Bruce Cooper,
Brian Schmidt,
Dale Langford,
Janine Cataldo,
Bradley E. Aouizerat
et al.
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425-437
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Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial
09 April 2012
Abstract: Patients with advanced cancer who have pain that responds poorly to opioid therapy pose a clinical challenge. Nabiximols (Nabiximols is the US Adopted Name [USAN] for Sativex [GW Pharma Ltd,...
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Russell K. Portenoy,
Elena Doina Ganae-Motan,
Silvia Allende,
Ronald Yanagihara,
Lauren Shaiova,
Sharon Weinstein,
Robert McQuade,
Stephen Wright,
Marie T. Fallon
et al.
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438-449
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Effects of Motor Cortex Modulation and Descending Inhibitory Systems on Pain Thresholds in Healthy Subjects
20 April 2012
Abstract: Pain modulation can be achieved using neuromodulatory tools that influence various levels of the nervous system. Transcranial direct current stimulation (tDCS), for instance, has been shown ...
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Jay S. Reidler,
Mariana E. Mendonca,
Marcus B. Santana,
Xiaoen Wang,
Robert Lenkinski,
Andrea F. Motta,
Serge Marchand,
Lydia Latif,
Felipe Fregni
et al.
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450-458
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Influence of Estrogen Levels on Thermal Perception, Pain Thresholds, and Pain Tolerance: Studies on Women Undergoing in Vitro Fertilization
05 April 2012
Abstract: We examined the relationship between estrogen and pain in women undergoing in vitro fertilization (IVF). Quantitative sensory tests (QST) were performed twice during the IVF-regimen: once du...
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Kent D. Stening,
Göran Berg,
Mats Hammar,
Helene Voster,
Olle Eriksson,
Åsa Amandusson,
Anders Blomqvist
et al.
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459-466
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Negative Emotional Responses Elicited by the Anticipation of Pain in Others: Psychophysiological Evidence
Abstract: Limited evidence is available about factors influencing observers’ anticipatory emotional responses to another’s pain. We investigated fear and distress towards the threat of pain in others,...
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Line Caes,
Katarzyna Uzieblo,
Geert Crombez,
Lies De Ruddere,
Tine Vervoort,
Liesbet Goubert
et al.
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467-476
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Autonomic Nervous System Function in Young Children With Functional Abdominal Pain or Irritable Bowel Syndrome
23 April 2012
Abstract: Adults with irritable bowel syndrome (IBS) have been reported to have alterations in autonomic nervous system function as measured by vagal activity via heart rate variability. Whether the s...
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Monica Jarrett,
Margaret Heitkemper,
Danita Czyzewski,
Lonnie Zeltzer,
Robert J. Shulman
et al.
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477-484
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Inhibitor Kappa B Kinase Beta Dependent Cytokine Upregulation in Nociceptive Neurons Contributes to Nociceptive Hypersensitivity After Sciatic Nerve Injury
Abstract: Inhibitor kappa B kinase (IKK)-mediated nuclear factor-kappa B (NF-κB) activation is a major pathway for transcriptional control of various pro-inflammatory factors. We here assessed whether...
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Maike Kanngiesser,
Annett Häussler,
Thekla Myrczek,
Nele Küsener,
Hee-Young Lim,
Gerd Geisslinger,
Ellen Niederberger,
Irmgard Tegeder
et al.
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485-497
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(+)-Naloxone, an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor, Reverses Multiple Models of Chronic Neuropathic Pain in Rats
23 April 2012
Abstract: Previous work demonstrated that both the opioid antagonist (-)-naloxone and the non-opioid (+)-naloxone inhibit toll-like receptor 4 (TLR4) signaling and reverse neuropathic pain expressed s...
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Susannah S. Lewis,
Lisa C. Loram,
Mark R. Hutchinson,
Chien-Ming Li,
Yingning Zhang,
Steven F. Maier,
Yong Huang,
Kenner C. Rice,
Linda R. Watkins
et al.
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498-506
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Intact Cognitive Inhibition in Patients With Fibromyalgia but Evidence of Declined Processing Speed
Abstract: Patients with fibromyalgia frequently report cognitive complaints. In this study we examined performance on 2 cognitive inhibition tests, the Stroop Color-Word Test (SCWT) and the Multi-Sour...
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Dieuwke S. Veldhuijzen,
Stephanie F.V. Sondaal,
Joukje M. Oosterman
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507-515
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| Letters to the Editor |
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The Association Between Polymorphisms in Serotonin-Related Genes and Pain Modulation Might Be of Importance for the Pathogenesis of Sudden Infant Death Syndrome
While reading the excellent article, “Association Between Polymorphisms in Serotonin and Dopamine-Related Genes and Endogenous Pain Modulation” by Treister et al in a recent edition of the Journal, I ...
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Michael Klintschar
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516
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Reply
We wish to thank Dr. Klintschar for his Letter to the Editor in response to our article entitled on “Association between polymorphisms in serotonin and dopamine-related genes and endogenous pain modul...
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Roi Treister,
Dorit Pud,
Richard P. Ebstein,
Efrat Laiba,
Yael Raz,
Edith Gershon,
May Haddad,
Elon Eisenberg
et al.
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517-518
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| Frontmatter |
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Masthead
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A5
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Editorial Board
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A6
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Table of Contents
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A12
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