Issue Highlights
- Craving of Prescription Opioids in Patients with Chronic Pain: A Longitudinal Outcomes Trial
Little is known about whether chronic pain patients treated with opioids experience craving for their medications, whether contextual cues may influence craving, or if there is a relationship between craving and medication compliance. This report studied craving in 62 patients who were at low or high risk for opioid misuse, while they were enrolled in a program to improve medication compliance. Findings indicate that craving is a potentially important psychological construct. Targeting craving may be an important intervention to decrease misuse and improve prescription opioid compliance.
- Muscle pain differentially modulates short-interval intra-cortical inhibition and intra-cortical facilitation in primary motor cortex
Excitability of the motor cortex can be suppressed during muscle pain, yet the mechanisms are largely unknown. Short-interval intra-cortical inhibition (SICI) and intra-cortical facilitation (ICF) were examined as possible candidate mechanisms to underpin this change. Results indicate that muscle pain differentially modulates SICI and ICF. Although the functional relevance is unknown, the authors hypothesize that decreased facilitation and increased inhibition may contribute to the restriction of movement of a painful body part.
April 2011 APS Abstract Issue
APS Guidelines
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Resolution of Acute Pain Following Discharge From the Emergency Department: The Acute Pain Trajectory30 January 2012
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Evidence That Spinal Astrocytes but Not Microglia Contribute to the Pathogenesis of Paclitaxel-Induced Painful Neuropathy30 January 2012
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Concurrent Use of Alcohol and Sedatives Among Persons Prescribed Chronic Opioid Therapy: Prevalence and Risk Factors30 January 2012
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Multicomponent Cognitive-Behavioral Group Therapy With Hypnosis for the Treatment of Fibromyalgia: Long-Term Outcome30 January 2012
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Lack of Endogenous Pain Inhibition During Exercise in People With Chronic Whiplash Associated Disorders: An Experimental Study27 January 2012









