Current Issue February 2012, Vol. 10, No. 2

Editor's Essential Reading

Original Articles—Liver, Pancreas, and Biliary Tract

  • Factors Related to Fatigue in Patients With Cirrhosis Before and After Liver Transplantation 

    Evangelos Kalaitzakis, Axel Josefsson, Maria Castedal, Pia Henfridsson, Maria Bengtsson, Irene Hugosson, Bengt Andersson, Einar Björnsson

    Fatigue is common among patients with cirrhosis and associated with impaired quality of life. Psychological distress, severity of cirrhosis, and low levels of cortisol determine general fatigue, whereas anemia and impaired renal function also contribute to physical fatigue. Physical fatigue remains of concern for patients who have received liver transplants for cirrhosis.

Issue Highlights

Endoscopy Corner

Brief Communication

Original Articles—Alimentary Tract

  • Travel-Associated Health Risks for Patients With Inflammatory Bowel Disease

    Patients with IBD have a higher rate of illness compared with controls during trips to industrialized countries, but not to developing or tropical regions. These findings indicate that most travel-associated illnesses stem from sporadic IBD flares rather than increased susceptibility to enteric infections.

Original Articles—Liver, Pancreas, and Biliary Tract

View Additional Issue Highlights

  • Isolated jejunal varices: a cause of occult gastrointestinal hemorrhage in a cirrhotic patient with mild portal hypertension
    30 January 2012

    Noam Shussman, Gadi Lalazar, Allan I. Bloom

  • Gastric acid suppression and C. difficile infection: Is there a causal connection?
    30 January 2012

    Sahil Khanna, Darrell S. Pardi

  • Immunoglobulin E Levels And Its Significance In Patients With Primary Sclerosing Cholangitis
    30 January 2012

    Udayakumar Navaneethan, Preethi G.K. Venkatesh, Ravi P. Kiran

  • Predicting Outcomes Following Restorative Proctocolectomy for Ulcerative Colitis
    30 January 2012

    Konstantinos A. Papadakis

  • Safety of cardiac surgery in cirrhotic patients: going to the heart of the matter
    30 January 2012

    Edoardo G. Giannini

  • Levels of Alanine Aminotransferase Confound Use of Transient Elastography to Diagnose Fibrosis in Patients with Chronic HCV Infection
    30 January 2012

    Elliot B. Tapper, Eric B. Cohen, Keyur Patel, Bruce Bacon, Stuart Gordon, Eric Lawitz, David Nelson, Imad A. Nasser, Tracy Challies, Nezam Afdhal

  • Factors Associated with Persistant and Non-Persistant Chronic Constipation, Over 20 Years
    30 January 2012

    Rok Seon Choung, G. Richard. Locke, Enrique Rey, Cathy D. Schleck, Charles Baum, Alan R. Zinsmeister, Nicholas J. Talley

  • Efficacy and Safety of Anticoagulation on Patients with Cirrhosis and Portal Vein Thrombosis
    30 January 2012

    María Gabriela Delgado, Susana Seijo, Ismael Yepes, Linette Achécar, Maria Vega Catalina, Ángeles García-Criado, Juan G. Abraldes, Joaquín de la Peña, Rafael Bañares, Agustín Albillos, Jaume Bosch, Juan Carlos García-Pagán

  • Increased Numbers of Eosinophils, Rather than Only Etiology, Predict Histologic Changes in Patients with Esophageal Eosinophilia
    30 January 2012

    Srividya Sridhara, Karthik Ravi, Thomas C. Smyrk, Hirohito Kita, Gail M. Kephart, Catherine Weiler, David A. Katzka

  • Risk of Colorectal Cancer in Patients with Ulcerative Colitis: a Meta-Analysis of Population-Based Cohort Studies
    30 January 2012

    Tine Jess, Christine Rungoe, Laurent Peyrin-Biroulet

  • View More Articles in Press...

On the Cover

Cover Image

See our companion journal, Gastroenterology also published by Elsevier.

Notices

Clinical Gastroenterology and Hepatology is published by Elsevier for the AGA Institute.



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Image of the Week

A giant abdominal mass: fecaloma Resection of the descending and sigmoid colons, manual extraction of the remainder of the fecalomas from the rectum, and terminal colostomy performed following Hartmann's technique.

2 videos:

Dr. Ganapathy Prasad discusses his manuscript "Safety of Prior Endoscopic Mucosal Resection in Patients Receiving Radiofrequency Ablation of Barrett's Esophagus."
Video--flashvideo1cgh--http://www.youtube.com/v/i2bhZC4TmYc
Dr. Aldo Montano-Loza discusses his manuscript "Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis."
Video--flashvideo2cgh--http://www.youtube.com/v/BdrXDtyRNOI

Education Practice

Diagnosis of the Zollinger-Ellison Syndrome

A 42-year-old man is referred to you for evaluation of possible Zollinger-Ellison syndrome (ZES). He gives an 8-year history of heartburn, for which he has been receiving increasing doses of proton pump inhibitor (PPI) therapy. Over the past few months he has noted worsening symptoms of heartburn and regurgitation, especially at night or after large meals.

Practice Management

What to Do With My Ambulatory Surgery Center

If the clock could be turned back to 2007, to a time before the real estate bubble burst and the stock market crashed, most of us would take the opportunity to move our vulnerable assets to safer harbors. Just think of how much more you could buy today with that money if you only had it. Well, health care is sitting in 2007 today.

Editorial

Fatigue in Cirrhosis: Is Transplant the Answer?

Fatigue is a complex symptom that encompasses a range of complaints including malaise, exhaustion, lethargy, and loss of motivation and social interest. Chronic fatigue is common in the general population, affecting up to 20%. Many chronic diseases are associated with fatigue including rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis.