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Cover 1 page CO1 Full-Text PDF (182 KB)
This Month in Gastroenterology Laura Harrell, Eugene B. Chang pages 625-626 Preview | Full Text | Full-Text PDF (166 KB)
Gastroenterology News
New Rotavirus Vaccines Safe and Effective in Large Clinical Trials Les Lang pages 627-628 Preview | Full Text | Full-Text PDF (65 KB)
Pledges of $1.9 Billion at Avian Influenza Conference Les Lang page 628 Preview | Full Text | Full-Text PDF (44 KB)
Robert Sandler Elected AGA Vice President Les Lang pages 628-629 Preview | Full Text | Full-Text PDF (79 KB)
Comment from the editor
Gastrointestinal Surgery for Obesity: A Question of Life and Death and Expertise Samuel Klein page 630 Preview | Full Text | Full-Text PDF (52 KB)
Image of the Month
Image of the Month: David M. Warshauer, Section Editor D.R. Gaya, A.K. Foulis, A.J. Morris page 631 Preview | Full Text | Full-Text PDF (238 KB)
Rapid Communication
Peginterferon Alfa-2b Therapy in Acute Hepatitis C: Impact of Onset of Therapy on Sustained Virologic Response Sanaa M. Kamal, Amr E. Fouly, Refaat R. Kamel, Bridgette Hockenjos, Ahmed Al Tawil, Khalifa E. Khalifa, Qi He, Margaret J. Koziel, Khairy M. El Naggar, Jens Rasenack, Nezam H. Afdhal pages 632-638 Abstract | Full Text | Full-Text PDF (243 KB)
Clinical - Alimentary tract
Obesity: A Challenge to Esophagogastric Junction Integrity, 13 December 2005 John E. Pandolfino, Hashem B. El–Serag, Qing Zhang, Nimeesh Shah, Sudip K. Ghosh, Peter J. Kahrilas pages 639-649 Abstract | Full Text | Full-Text PDF (692 KB)
Predictors of Crohn’s Disease, 13 December 2005 Laurent Beaugerie, Philippe Seksik, Isabelle Nion–Larmurier, Jean–Pierre Gendre, Jacques Cosnes pages 650-656 Abstract | Full Text | Full-Text PDF (150 KB)
Biofeedback Is Superior to Laxatives for Normal Transit Constipation Due to Pelvic Floor Dyssynergia, 23 November 2005 Giuseppe Chiarioni, William E. Whitehead, Vincenzo Pezza, Antonio Morelli, Gabrio Bassotti pages 657-664 Abstract | Full Text | Full-Text PDF (303 KB)
Decrease in Mortality in Lynch Syndrome Families Because of Surveillance, 01 December 2005 Andrea E. de Jong, Yvonne M.C. Hendriks, Jan H. Kleibeuker, Sybrand Y. de Boer, Annemieke Cats, Gerrit Griffioen, Fokko M. Nagengast, Frits G. Nelis, Matti A. Rookus, Hans F.A. Vasen pages 665-671 Abstract | Full Text | Full-Text PDF (111 KB)
The Aer-O-Scope: Proof of Concept of a Pneumatic, Skill-Independent, Self-Propelling, Self-Navigating Colonoscope, 13 December 2005 Boris Vucelic, Douglas Rex, Roland Pulanic, Jorge Pfefer, Irena Hrstic, Bernard Levin, Zamir Halpern, Nadir Arber pages 672-677 Abstract | Full Text | Full-Text PDF (425 KB)
Clinical - Liver, Pancreas, and Biliary Tract
Predicting Cirrhosis Risk Based on the Level of Circulating Hepatitis B Viral Load, 23 November 2005 Uchenna H. Iloeje, Hwai–I. Yang, Jun Su, Chin–Lan Jen, San–Lin You, Chien–Jen Chen, The Risk Evaluation of Viral Load Elevation and Associated Liver Disease/Cancer-In HBV (the REVEAL-HBV) Study Group pages 678-686 Abstract | Full Text | Full-Text PDF (181 KB)
Measurement of Serum Acetaminophen–Protein Adducts in Patients With Acute Liver Failure Timothy J. Davern, Laura P. James, Jack A. Hinson, Julie Polson, Anne M. Larson, Robert J. Fontana, Ezmina Lalani, Santiago Munoz, A. Obaid Shakil, William M. Lee, The Acute Liver Failure Study Group pages 687-694 Abstract | Full Text | Full-Text PDF (253 KB)
HLA-DRB1 Donor-Recipient Mismatch Affects the Outcome of Hepatitis C Disease Recurrence After Liver Transplantation, 23 November 2005 Luca Saverio Belli, Patrizia Burra, Francesca Poli, Alberto Battista Alberti, Enrico Silini, Claudio Zavaglia, Stefano Fagiuoli, Daniela Prando, Alejandro Espadas de Arias, Sara Boninsegna, Carmine Tinelli, Mario Scalamogna, Luciano de Carlis, Giovambattista Pinzello pages 695-702 Abstract | Full Text | Full-Text PDF (158 KB)
Molecular Tracing of the Global Hepatitis C Virus Epidemic Predicts Regional Patterns of Hepatocellular Carcinoma Mortality Yasuhito Tanaka, Fuat Kurbanov, Shuhei Mano, Etsuro Orito, Victor Vargas, Juan I. Esteban, Man–Fung Yuen, Ching–Lung Lai, Anna Kramvis, Michael C. Kew, Heidi E. Smuts, Sergey V. Netesov, Harvey J. Alter, Masashi Mizokami pages 703-714 Abstract | Full Text | Full-Text PDF (398 KB)
Ito of Ito’s Cells William Haubrich page 714 Preview | Full Text | Full-Text PDF (60 KB)
Excellent Long-Term Survival in Patients With Primary Biliary Cirrhosis and Biochemical Response to Ursodeoxycholic Acid Albert Parés, Llorenç Caballería, Juan Rodés pages 715-720 Abstract | Full Text | Full-Text PDF (120 KB)
Basic - Alimentary Tract
Antisense Inhibition of Entamoeba histolytica Cysteine Proteases Inhibits Colonic Mucus Degradation, 23 November 2005 Darcym Moncada, Kathy Keller, Serge Ankri, David Mirelman, Kris Chadee pages 721-730 Abstract | Full Text | Full-Text PDF (643 KB)
Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells, 13 December 2005 Silvia Resta–Lenert, Kim E. Barrett pages 731-746 Abstract | Full Text | Full-Text PDF (1196 KB)
All-Trans Retinoic Acid Induces XAF1 Expression Through an Interferon Regulatory Factor-1 Element in Colon Cancer, 13 December 2005 Jide Wang, Ying Peng, Yun Wei Sun, Hua He, Senlin Zhu, Xiaomeng An, Ming Li, Marie C.M. Lin, Bing Zou, Harry Hua–Xiang Xia, Bo Jiang, Annie O.O. Chan, Man Fung Yuen, Hsiang Fu Kung, Benjamin C.Y. Wong pages 747-758 Abstract | Full Text | Full-Text PDF (949 KB)
Reduced Stem Cell Factor Links Smooth Myopathy and Loss of Interstitial Cells of Cajal in Murine Diabetic Gastroparesis, 28 December 2005 Viktor J. Horváth, Harsha Vittal, Andrea Lörincz, Hui Chen, Graça Almeida–Porada, Doug Redelman, Tamás Ördög pages 759-770 Abstract | Full Text | Full-Text PDF (1881 KB)
Brain-Derived Neurotrophic Factor Augments Peristalsis by Augmenting 5-HT and Calcitonin Gene-Related Peptide Release, 28 December 2005 John R. Grider, Barbara E. Piland, Melisa A. Gulick, Li Ya Qiao pages 771-780 Abstract | Full Text | Full-Text PDF (204 KB)
Basic-Liver, Pancreas, and Biliary Tract
Fatty Acid Ethyl Esters Cause Pancreatic Calcium Toxicity via Inositol Trisphosphate Receptors and Loss of ATP Synthesis, 28 December 2005 David N. Criddle, John Murphy, Gregorio Fistetto, Stephanie Barrow, Alexei V. Tepikin, John P. Neoptolemos, Robert Sutton, Ole H. Petersen pages 781-793 Abstract | Full Text | Full-Text PDF (2184 KB)
Src Homology 3 Domain of Hepatitis C Virus NS5A Protein Interacts With Bin1 and Is Important for Apoptosis and Infectivity, 28 December 2005 Santosh K. Nanda, David Herion, T. Jake Liang pages 794-809 Abstract | Full Text | Full-Text PDF (1005 KB)
Kupffer Cells Abrogate Cholestatic Liver Injury in Mice, 23 November 2005 Stephan Gehring, Elizabeth M. Dickson, Maryann E. San Martin, Nico van Rooijen, Elaine F. Papa, Mark W. Harty, Thomas F. Tracy, Stephen H. Gregory pages 810-822 Abstract | Full Text | Full-Text PDF (4581 KB)
Hepatitis B Virus Replication Is Regulated by the Acetylation Status of Hepatitis B Virus cccDNA-Bound H3 and H4 Histones, 11 January 2006 Teresa Pollicino, Laura Belloni, Giuseppina Raffa, Natalia Pediconi, Giovanni Squadrito, Giovanni Raimondo, Massimo Levrero pages 823-837 Abstract | Full Text | Full-Text PDF (689 KB)
Defective RhoA/Rho-Kinase Signaling Contributes to Vascular Hypocontractility and Vasodilation in Cirrhotic Rats, 01 December 2005 Martin Hennenberg, Erwin Biecker, Jonel Trebicka, Kerstin Jochem, Qi Zhou, Martina Schmidt, Karl H. Jakobs, Tilman Sauerbruch, Jörg Heller pages 838-854 Abstract | Full Text | Full-Text PDF (748 KB)
Loss of the Major Duodenal Papilla Results in Brown Pigment Biliary Stone Formation in Pdx1 Null Mice, 01 December 2005 Akihisa Fukuda, Yoshiya Kawaguchi, Kenichiro Furuyama, Sota Kodama, Takeshi Kuhara, Masashi Horiguchi, Masayuki Koizumi, Koji Fujimoto, Ryuichiro Doi, Christopher V.E. Wright, Tsutomu Chiba pages 855-867 Abstract | Full Text | Full-Text PDF (1194 KB)
Polyclonal T-Cell Responses to Cytochrome P450IID6 Are Associated With Disease Activity in Autoimmune Hepatitis Type 2, 13 December 2005 Yun Ma, Dimitrios P. Bogdanos, Munther J. Hussain, James Underhill, Sanjay Bansal, Maria Serena Longhi, Paul Cheeseman, Giorgina Mieli–Vergani, Diego Vergani pages 868-882 Abstract | Full Text | Full-Text PDF (995 KB)
Hepatitis C Virus Core Protein Is a Potent Inhibitor of RNA Silencing-Based Antiviral Response, 28 December 2005 Yue Wang, Naoya Kato, Amarsanaa Jazag, Narayan Dharel, Motoyuki Otsuka, Hiroyoshi Taniguchi, Takao Kawabe, Masao Omata pages 883-892 Abstract | Full Text | Full-Text PDF (367 KB)
Case Report
Mitochondrial Neurogastrointestinal Encephalomyopathy: Evidence of Mitochondrial DNA Depletion in the Small Intestine, 11 January 2006 Carla Giordano, Mariangela Sebastiani, Giuseppe Plazzi, Claudia Travaglini, Patrizio Sale, Marcello Pinti, Andrea Tancredi, Rocco Liguori, Pasquale Montagna, Marzio Bellan, Maria Lucia Valentino, Andrea Cossarizza, Michio Hirano, Giulia d’Amati, Valerio Carelli pages 893-901 Abstract | Full Text | Full-Text PDF (619 KB)
Microarrays and Other New Technologies
Identification of Mouse Genes With Highly Specific Expression Patterns in Differentiated Intestinal Epithelium, 28 December 2005 Natalia Schröder, Aravind Sekhar, Insa Geffers, Julia Müller, Oliver Dittrich–Breiholz, Michael Kracht, Jochen Wedemeyer, Achim Gossler pages 902-907 Abstract | Full Text | Full-Text PDF (240 KB) | Bonus Content
Special reports and reviews
Hepatocanalicular Transport Defects: Pathophysiologic Mechanisms of Rare Diseases, 04 October 2005 Ronald P.J. Oude Elferink, Coen C. Paulusma, Albert K. Groen pages 908-925 Abstract | Full Text | Full-Text PDF (516 KB)
New concepts in Gastroenterology
Of Cilia and Cysts: Modeling Pancreatic Polycystic Disease Klaus H. Kaestner pages 926-928 Preview | Full Text | Full-Text PDF (147 KB)
CME Activity
Continuing Medical Education Exams 1: March 2006 Eugene Chang, Laura Harrell page 929 Full-Text PDF (54 KB)
Continuing Medical Education Exams 2: March 2006: Biofeedback Is Superior to Laxatives for Normal Transit Constipation due to Pelvic Floor Dyssynergia G. Chiarioni, W.E. Whitehead, V. Pezza, A. Morelli, G. Bassotti page 930 Full-Text PDF (54 KB)
Continuing Medical Education Exams 3: March 2006: The Aer-O-Scope: Proof of Concept of a Pneumatic, Skill Independent, Self Propelling, Self Navigating Colonoscope B. Vucelic, D. Rex, R. Pulanic, J. Pfefer, I. Hrstic, B. Levin, Z. Halpren, N. Arber page 930 Full-Text PDF (53 KB)
Continuing Medical Education Exams 4: March 2006: Predicting Cirrhosis Risk Based on the Level of Circulating Hepatitis B Viral Load U.H. Iloeje, H.–I. Yang, J. Su, C.–L. Jen, S.–L. You, C.–J. Chen page 930 Full-Text PDF (54 KB)
Continuing Medical Education Exams 5: March 2006: Hepatocanalicular Transport Defects: Pathophysiological Mechanisms of Rare Diseases R.P.J. Oude Elferink, C.C. Paulusma, A.K. Groen page 931 Full-Text PDF (47 KB)
Continuing Medical Education Exam 6: March 2006: AGAI Medical Position Statement and Technical Review G.R. Lichtenstein pages 932-934 Full-Text PDF (52 KB)
American Gastroenterological Association
American Gastroenterological Association Institute Medical Position Statement on Corticosteroids, Immunomodulators, and Infliximab in Inflammatory Bowel Disease Gary R. Lichtenstein, Maria T. Abreu, Russell Cohen, William Tremaine pages 935-939 Preview | Full Text | Full-Text PDF (76 KB)
American Gastroenterological Association Institute Technical Review on Corticosteroids, Immunomodulators, and Infliximab in Inflammatory Bowel Disease Gary R. Lichtenstein, Maria T. Abreu, Russell Cohen, William Tremaine pages 940-987 Preview | Full Text | Full-Text PDF (490 KB)
Editorials
Pressure Details From the Weight-Challenged Gastroesophageal Junction: More Than the Usual Suspects Radu Tutuian, Donald O. Castell pages 988-989 Preview | Full Text | Full-Text PDF (72 KB)
Hepatitis B Virus Replication x Time Equals Trouble Robert Perrillo pages 989-991 Preview | Full Text | Full-Text PDF (82 KB)
Fatty Acid Ethyl Esters–Alcohol’s Henchmen in the Pancreas? Minoti V. Apte, Ron C. Pirola, Jeremy S. Wilson pages 992-995 Preview | Full Text | Full-Text PDF (95 KB)
Hepatitis C Virus NS5A Protein–A Master Regulator? Gyongyi Szabo pages 995-999 Preview | Full Text | Full-Text PDF (156 KB)
Selected Summaries
Environment, genetics, and fish? Answers to the cancer riddle Aram N. Demirjian, Mark P. Callery pages 1000-1001 Preview | Full Text | Full-Text PDF (62 KB)
GRK2 makes trouble: A no-No in portal hypertension David Semela, Daniel A. Langer, Vijay Shah pages 1001-1003 Preview | Full Text | Full-Text PDF (62 KB)
Reply Songling Liu, Don C. Rockey page 1003 Preview | Full Text | Full-Text PDF (46 KB)
Phospholipid in UC: Novel, safe and works—is it too good to be true? Nick M. Croft pages 1003-1004 Preview | Full Text | Full-Text PDF (55 KB)
Reply Wolfgang Stremmel pages 1004-1005 Preview | Full Text | Full-Text PDF (52 KB)
Prophylaxis with beta blockers as a performance measure of quality health care in cirrhosis Jayant A. Talwalkar pages 1005-1007 Preview | Full Text | Full-Text PDF (60 KB)
Cyst fluid analysis to diagnose pancreatic cystic lesions: An as yet unfulfilled promise Mario Pelaez-Luna, Suresh T. Chari pages 1007-1009 Preview | Full Text | Full-Text PDF (61 KB)
Reply Laurens A. Van der Waaij, Hendrik M. Van Dullemen, Robert J. Porte page 1009 Preview | Full Text | Full-Text PDF (37 KB)
Print and Media Reviews
Digestive Endoscopy in the Second Millennium: From the Lichtlleiter to Echoendoscopy William S. Haubrich page 1010 Preview | Full Text | Full-Text PDF (40 KB)
Textbook of Pediatric Gastroenterology and Nutrition Gary J. Russell pages 1010-1011 Preview | Full Text | Full-Text PDF (44 KB)
Correspondence
Projected National Impact of Colorectal Cancer Screening on Clinical and Economic Outcomes and Health Services Demand Tom Zarchy page 1012 Preview | Full Text | Full-Text PDF (62 KB)
Reply Uri Ladabaum page 1012 Preview | Full Text | Full-Text PDF (62 KB)
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