Best Basic and Clinical Research of 2007

At this year's Digestive Disease Week, editors Anil K. Rustgi, MD, and C. Mel Wilcox, MD, presented the best basic and clinical research published in Gastroenterology and Clinical Gastroenterology and Hepatology.

Gastroenterology Plenary Papers

Tracking Down the Stem Cells of the Intestine: Strategies to Identify Adult Stem Cells
Nick Barker, Hans Clevers
Gastroenterology, 2007;133:1755-1760

Severe Intestinal Obstruction on Induced Smooth Muscle-Specific Ablation of the Transcription Factor SRF in Adult Mice
Meike Angstenberger, Jörg W. Wegener, Bernd J. Pichler, Martin S. Judenhofer, Susanne Feil, Siegfried Alberti, Robert Feil, Alfred Nordheim
Gastroenterology, 2007;133:1948-1959

Inducible Mouse Model of Chronic Intestinal Pseudo-Obstruction by Smooth Muscle-Specific Inactivation of the SRF Gene
Mathias Mericskay, Jocelyne Blanc, Eva Tritsch, Raphael Moriez, Philippe Aubert, Michel Neunlist, Robert Feil, Zhenlin Li
Gastroenterology, 2007;133:1960-1970

Visceral Neuropathy and Intestinal Pseudo-Obstruction in a Murine Model of a Nuclear Inclusion Disease
Christine M. Clarke, Cara Plata, Bonnie Cole, Karen Tsuchiya, Albert R. La Spada, Raj P. Kapur
Gastroenterology, 2007;133:1971-1978

Deciphering Chronic Intestinal Pseudo-Obstruction: Do Mice Help to Solve the Riddle?
Roberto De Giorgio, Marco Seri, Guillaume van Eys
Gastroenterology, 2007;133:2052-2055

Clinical Gastroenterology and Hepatology Plenary Papers

Functional Imaging of Colonic Mucosa With a Fibered Confocal Microscope for Real-Time In Vivo Pathology
Thomas D. Wang, Shai Friedland, Peyman Sahbaie, Roy Soetikno, Pei-Lin Hsiung, Jonathan T.C. Liu, James M. Crawford, Christopher H. Contag
Clinical Gastroenterology and Hepatology, 2007;5:1300-1305

Confocal Laser Endomicroscopy for In Vivo Diagnosis of Early Squamous Cell Carcinoma in the Esophagus
Oliver Pech, Thomas Rabenstein, Hendrik Manner, Maria C. Petrone, Jürgen Pohl, Michael Vieth, Manfred Stolte, Christian Ell
Clinical Gastroenterology and Hepatology, 2008;6:89-94

Confocal Endomicroscopy in Ulcerative Colitis: Differentiating Dysplasia-Associated Lesional Mass and Adenoma-Like Mass
David P. Hurlstone, Mike Thomson, S. Brown, Nick Tiffin, Simon S. Cross, Michael D. Hunter
Clinical Gastroenterology and Hepatology, 2007;5:1235-1241

In Vivo Histopathology for Detection of Gastrointestinal Neoplasia With a Portable, Confocal Miniprobe: An Examiner Blinded Analysis
Alexander Meining, Dieter Saur, Monther Bajbouj, Valentin Becker, Eric Peltier, Heinz Höfler, Claus Hann von Weyhern, Roland M. Schmid, Christian Prinz
Clinical Gastroenterology and Hepatology, 2007;5:1261-1267

Correlation of FIBROSpect II With Histologic and Morphometric Evaluation of Liver Fibrosis in Chronic Hepatitis C
Keyur Patel, David R. Nelson, Don C. Rockey, Nezam H. Afdhal, Katie M. Smith, Esther Oh, Keith Hettinger, Marc Vallée, Anouk Dev, Margaret Smith-Riggs, John G. McHutchison
Clinical Gastroenterology and Hepatology, 2007;6:242-247

Assessment of Hepatic Fibrosis With Magnetic Resonance Elastography
Meng Yin, Jayant A. Talwalkar, Kevin J. Glaser, Armando Manduca, Roger C. Grimm, Phillip J. Rossman, Jeff L. Fidler, Richard L. Ehman
Clinical Gastroenterology and Hepatology, 2007;5:1207-1213

Ultrasound-Based Transient Elastography for the Detection of Hepatic Fibrosis: Systematic Review and Meta-analysis
Jayant A. Talwalkar, David M. Kurtz, Scott J. Schoenleber, Colin P. West, Victor M. Montori
Clinical Gastroenterology and Hepatology, 2007;5:1214-1220