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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Surgical Management of Early-Stage Non-small Cell Lung Carcinoma and the Present and Future Roles of Adjuvant Therapy: A Review for the Radiation Oncologist
DOI: 10.1016/j.ijrobp.2012.03.018
We review the evidence for optimal surgical management and adjuvant therapy for patients with stages I and II non-small cell lung cancer (NSCLC) along with factors associated with increased risks of r...
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Laura Medford-Davis,
Malcom DeCamp,
Abram Recht,
John Flickinger,
Chandra P. Belani,
John Varlotto
et al.
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Review article
(In Press Corrected Proof)
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24 May 2012 |
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Dose-Guided Radiotherapy: Potential Benefit of Online Dose Recalculation for Stereotactic Lung Irradiation in Patients with Non-Small-Cell Lung Cancer
DOI: 10.1016/j.ijrobp.2011.12.055
Purpose: To determine whether dose-guided radiotherapy (i.e., online recalculation and evaluation of the actual dose distribution) can improve decision making for lung cancer patients treated with ste...
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Dominique C. van Rooijen,
Niek van Wieringen,
Gjenna Stippel,
Johannes Crezee,
Caro C.E. Koning,
Arjan Bel
et al.
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Full-length article
(In Press Corrected Proof)
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24 May 2012 |
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From the Lost Radium Files: Misadventures in the Absence of Training, Regulation, and Accountability
DOI: 10.1016/j.ijrobp.2012.01.057
Purpose: Radium was the foundation of brachytherapy in the early decades of the 20th century. Despite being a most precious and perilous substance, it was mislaid with surprising frequency. This essay...
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Jesse N. Aronowitz,
Joel O. Lubenau
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Full-length article
(In Press Corrected Proof)
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23 May 2012 |
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HSPB1 Gene Polymorphisms Predict Risk of Mortality for US Patients after Radio(chemo)therapy for Non-Small Cell Lung Cancer
DOI: 10.1016/j.ijrobp.2012.03.032
Purpose: We investigated potential associations between single-nucleotide polymorphisms (SNPs) in the heat shock protein beta-1 (HSPB1) gene and overall survival in US patients with non-small cell lun...
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Ting Xu,
Qingyi Wei,
Jose Luis Lopez Guerra,
Li-E Wang,
Zhensheng Liu,
Daniel Gomez,
Michael O'Reilly,
Steven Hsesheng Lin,
Yan Zhuang,
Lawrence B. Levy,
Radhe Mohan,
Honghao Zhou,
Zhongxing Liao
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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Visual Outcomes in Pediatric Optic Pathway Glioma After Conformal Radiation Therapy
DOI: 10.1016/j.ijrobp.2011.10.067
Purpose: To assess visual outcome prospectively after conformal radiation therapy (CRT) in children with optic pathway glioma. Methods and Materials: We used CRT to treat optic pathway glioma in 20 ch...
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Richard M. Awdeh,
Erin N. Kiehna,
Richard D. Drewry,
Natalie C. Kerr,
Barrett G. Haik,
Shengjie Wu,
Xiaoping Xiong,
Thomas E. Merchant
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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International Spine Radiosurgery Consortium Consensus Guidelines for Target Volume Definition in Spinal Stereotactic Radiosurgery
DOI: 10.1016/j.ijrobp.2012.03.009
Purpose: Spinal stereotactic radiosurgery (SRS) is increasingly used to manage spinal metastases. However, target volume definition varies considerably and no consensus target volume guidelines exist....
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Brett W. Cox,
Daniel E. Spratt,
Michael Lovelock,
Mark H. Bilsky,
Eric Lis,
Samuel Ryu,
Jason Sheehan,
Peter C. Gerszten,
Eric Chang,
Iris Gibbs,
Scott Soltys,
Arjun Sahgal,
Joe Deasy,
John Flickinger,
Mubina Quader,
Stefan Mindea,
Yoshiya Yamada
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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Pleural Intensity-Modulated Radiotherapy for Malignant Pleural Mesothelioma
DOI: 10.1016/j.ijrobp.2011.09.027
Purpose: In patients with malignant pleural mesothelioma who are unable to undergo pneumonectomy, it is difficult to deliver tumoricidal radiation doses to the pleura without significant toxicity. We ...
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Kenneth E. Rosenzweig,
Marjorie G. Zauderer,
Benjamin Laser,
Lee M. Krug,
Ellen Yorke,
Camelia S. Sima,
Andreas Rimner,
Raja Flores,
Valerie Rusch
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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Combined Modality Treatment for PET-Positive Non-Hodgkin Lymphoma: Favorable Outcomes of Combined Modality Treatment for Patients With Non-Hodgkin Lymphoma and Positive Interim or Postchemotherapy FDG-PET
DOI: 10.1016/j.ijrobp.2012.01.060
Purpose: To evaluate outcomes of patients treated for aggressive non-Hodgkin lymphoma (NHL) with combined modality therapy based on [18F]fluoro-2-deoxy-2-d-glucose positron emission tomography (FDG-PE...
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Lia M. Halasz,
Heather A. Jacene,
Paul J. Catalano,
Annick D. Van den Abbeele,
Ann LaCasce,
Peter M. Mauch,
Andrea K. Ng
et al.
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Full-length article
(In Press Corrected Proof)
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21 May 2012 |
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Potential of Hybrid Computational Phantoms for Retrospective Heart Dosimetry After Breast Radiation Therapy: A Feasibility Study
DOI: 10.1016/j.ijrobp.2012.03.037
Purpose: Current retrospective cardiovascular dosimetry studies are based on a representative patient or simple mathematic phantoms. Here, a process of patient modeling was developed to personalize th...
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Alexandra Moignier,
Sylvie Derreumaux,
David Broggio,
Julien Beurrier,
Michel Chea,
Gilbert Boisserie,
Didier Franck,
Bernard Aubert,
Jean-Jacques Mazeron
et al.
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Full-length article
(In Press Corrected Proof)
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17 May 2012 |
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Risk of Radiation Retinopathy in Patients With Orbital and Ocular Lymphoma
DOI: 10.1016/j.ijrobp.2011.12.097
Purpose: Radiation retinopathy is a potential long-term complication of radiation therapy to the orbit. The risk of developing this adverse effect is dose dependent; however, the threshold is unclear....
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Megha Kaushik,
Jose S. Pulido,
Steven E. Schild,
Scott Stafford
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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No Effect of the Transforming Growth Factor β1 Promoter Polymorphism C-509T on TGFB1 Gene Expression, Protein Secretion, or Cellular Radiosensitivity
DOI: 10.1016/j.ijrobp.2012.01.090
Purpose: To study whether the promoter polymorphism (C-509T) affects transforming growth factor β1 gene (TGFB1) expression, protein secretion, and/or cellular radiosensitivity for both human lymphocyt...
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Sebastian Reuther,
Elisabeth Metzke,
Michael Bonin,
Cordula Petersen,
Ekkehard Dikomey,
Annette Raabe
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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Dose Escalation of Total Marrow Irradiation With Concurrent Chemotherapy in Patients With Advanced Acute Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation
DOI: 10.1016/j.ijrobp.2012.03.033
Purpose: We have demonstrated that toxicities are acceptable with total marrow irradiation (TMI) at 16 Gy without chemotherapy or TMI at 12 Gy and the reduced intensity regimen of fludarabine/melphala...
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Jeffrey Y.C. Wong,
Stephen Forman,
George Somlo,
Joseph Rosenthal,
An Liu,
Timothy Schultheiss,
Eric Radany,
Joycelynne Palmer,
Anthony Stein
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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Predictors of Toxicity After Image-guided High-dose-rate Interstitial Brachytherapy for Gynecologic Cancer
DOI: 10.1016/j.ijrobp.2012.01.085
Purpose: To identify predictors of grade 3-4 complications and grade 2-4 rectal toxicity after three-dimensional image-guided high-dose-rate (HDR) interstitial brachytherapy for gynecologic cancer. Me...
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Larissa J. Lee,
Akila N. Viswanathan
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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Identification and Characterization of a Small Inhibitory Peptide That Can Target DNA-PKcs Autophosphorylation and Increase Tumor Radiosensitivity
DOI: 10.1016/j.ijrobp.2012.01.092
Purpose: The DNA protein kinase catalytic subunit (DNA-PKcs) is one of the critical elements involved in the DNA damage repair process. Inhibition of DNA-PKcs results in hypersensitivity to ionizing r...
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Xiaonan Sun,
Chunying Yang,
Hai Liu,
Qi Wang,
Shi-Xiu Wu,
Xia Li,
Tian Xie,
Kathryn L. Brinkman,
Bin S. Teh,
E. Brian Butler,
Bo Xu,
Shu Zheng
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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A One-Step Cone-Beam CT-Enabled Planning-to-Treatment Model for Palliative Radiotherapy-From Development to Implementation
DOI: 10.1016/j.ijrobp.2012.01.025
Purpose: To develop a cone-beam computed tomography (CT)–enabled one-step simulation-to-treatment process for the treatment of bone metastases. Methods and Materials: A three-phase prospective study w...
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Rebecca K.S. Wong,
Daniel Letourneau,
Anita Varma,
Jean Pierre Bissonnette,
David Fitzpatrick,
Daniel Grabarz,
Christine Elder,
Melanie Martin,
Andrea Bezjak,
Tony Panzarella,
Mary Gospodarowicz,
David A. Jaffray
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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Dose-Effect Relationship in Chemoradiotherapy for Locally Advanced Rectal Cancer: A Randomized Trial Comparing Two Radiation Doses
DOI: 10.1016/j.ijrobp.2012.02.006
Purpose: Locally advanced rectal cancer represents a major therapeutic challenge. Preoperative chemoradiation therapy is considered standard, but little is known about the dose-effect relationship. Th...
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Anders Jakobsen,
John Ploen,
Té Vuong,
Ane Appelt,
Jan Lindebjerg,
Soren R. Rafaelsen
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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Role of Positron Emission Tomography-Computed Tomography in the Management of Anal Cancer
DOI: 10.1016/j.ijrobp.2011.10.048
Purpose: Pre- and post-treatment staging of anal cancer are often inaccurate. The role of positron emission tomograpy-computed tomography (PET-CT) in anal cancer is yet to be defined. The aim of the s...
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Massimiliano Mistrangelo,
Ettore Pelosi,
Marilena Bellò,
Umberto Ricardi,
Enrica Milanesi,
Paola Cassoni,
Massimo Baccega,
Claudia Filippini,
Patrizia Racca,
Adriana Lesca,
Fernando H. Munoz,
Gianluca Fora,
Andrea Skanjeti,
Francesca Cravero,
Mario Morino
et al.
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Full-length article
(In Press Corrected Proof)
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16 May 2012 |
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[18F]fluoromisonidazole and a New PET System With Semiconductor Detectors and a Depth of Interaction System for Intensity Modulated Radiation Therapy for Nasopharyngeal Cancer
DOI: 10.1016/j.ijrobp.2012.03.029
Purpose: The impact of a new type of positron emission tomography (New PET) with semiconductor detectors using 18F-labeled fluoromisonidazole (FMISO)-guided intensity modulated radiation therapy (IMRT...
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Koichi Yasuda,
Rikiya Onimaru,
Shozo Okamoto,
Tohru Shiga,
Norio Katoh,
Kazuhiko Tsuchiya,
Ryusuke Suzuki,
Wataru Takeuchi,
Yuji Kuge,
Nagara Tamaki,
Hiroki Shirato
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Short-Course Accelerated Radiotherapy in Palliative Treatment of Advanced Pelvic Malignancies: A Phase I Study
DOI: 10.1016/j.ijrobp.2011.10.081
Purpose: To define the maximum tolerated dose of a conformal short-course accelerated radiotherapy in patients with symptomatic advanced pelvic cancer. Methods and Materials: A phase I trial in 3 dose...
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Luciana Caravatta,
Gilbert D.A. Padula,
Gabriella Macchia,
Gabriella Ferrandina,
Pierluigi Bonomo,
Francesco Deodato,
Mariangela Massaccesi,
Samantha Mignogna,
Rosa Tambaro,
Marco Rossi,
Mariano Flocco,
Andrea Scapati,
Giovanni Scambia,
Fabio Pacelli,
Vincenzo Valentini,
Numa Cellini,
Alessio G. Morganti
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Monitoring of Circulating Tumor Cells and Their Expression of EGFR/Phospho-EGFR During Combined Radiotherapy Regimens in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
DOI: 10.1016/j.ijrobp.2012.02.009
Purpose: The numbers of circulating tumor cells (CTCs) and their expression/activation of epidermal growth factor receptor (EGFR) during the course of combined chemo- or bioradiotherapy regimens as po...
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Ingeborg Tinhofer,
Tsvetana Hristozova,
Carmen Stromberger,
Ulrich KeilhoIz,
Volker Budach
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Five-year Local Control in a Phase II Study of Hypofractionated Intensity Modulated Radiation Therapy With an Incorporated Boost for Early Stage Breast Cancer
DOI: 10.1016/j.ijrobp.2012.01.091
Purpose: Conventional radiation fractionation of 1.8-2 Gy per day for early stage breast cancer requires daily treatment for 6-7 weeks. We report the 5-year results of a phase II study of intensity mo...
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Gary M. Freedman,
Penny R. Anderson,
Richard J. Bleicher,
Samuel Litwin,
Tianyu Li,
Ramona F. Swaby,
Chang-Ming Charlie Ma,
Jinsheng Li,
Elin R. Sigurdson,
Deborah Watkins-Bruner,
Monica Morrow,
Lori J. Goldstein
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Normal Tissue Complication Probability Modeling of Radiation-Induced Hypothyroidism After Head-and-Neck Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.03.034
Purpose: To determine the dose-response relationship of the thyroid for radiation-induced hypothyroidism in head-and-neck radiation therapy, according to 6 normal tissue complication probability model...
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Mohsen Bakhshandeh,
Bijan Hashemi,
Seied Rabi Mehdi Mahdavi,
Alireza Nikoofar,
Maryam Vasheghani,
Anoshirvan Kazemnejad
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Skin-sparing Helical Tomotherapy vs 3D-conformal Radiotherapy for Adjuvant Breast Radiotherapy: In Vivo Skin Dosimetry Study
DOI: 10.1016/j.ijrobp.2012.01.086
Purpose: We investigated whether treatment-planning system (TPS)-calculated dose accurately reflects skin dose received for patients receiving adjuvant breast radiotherapy (RT) with standard three-dim...
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Lisa Capelle,
Heather Warkentin,
Marc MacKenzie,
Kurian Joseph,
Zsolt Gabos,
Nadeem Pervez,
Keith Tankel,
Susan Chafe,
John Amanie,
Sunita Ghosh,
Matthew Parliament,
Bassam Abdulkarim
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Optimal Timing for Assessment of Tumor Response to Neoadjuvant Chemoradiation in Patients With Rectal Cancer: Do All Patients Benefit From Waiting Longer Than 6 Weeks?
DOI: 10.1016/j.ijrobp.2012.01.096
Purpose: To estimate the metabolic activity of rectal cancers at 6 and 12 weeks after completion of chemoradiation therapy (CRT) by 2-[fluorine-18] fluoro-2-deoxy-d-glucose-labeled positron emission t...
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Rodrigo O. Perez,
Angelita Habr-Gama,
Guilherme P. São Julião,
Joaquim Gama-Rodrigues,
Afonso H.S. Sousa,
Fabio Guilherme Campos,
Antonio R. Imperiale,
Patricio B. Lynn,
Igor Proscurshim,
Sergio Carlos Nahas,
Carla Rachel Ono,
Carlos Alberto Buchpiguel
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Hearing Outcomes After Stereotactic Radiosurgery for Unilateral Intracanalicular Vestibular Schwannomas: Implication of Transient Volume Expansion
DOI: 10.1016/j.ijrobp.2012.03.036
Purpose: We evaluated the prognostic factors for hearing outcomes after stereotactic radiosurgery (SRS) for unilateral sporadic intracanalicular vestibular schwannomas (IC-VSs) as a clinical homogeneo...
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Young-Hoon Kim,
Dong Gyu Kim,
Jung Ho Han,
Hyun-Tai Chung,
In Kyung Kim,
Sang Woo Song,
Jeong-Hoon Park,
Jin Wook Kim,
Yong Hwy Kim,
Chul-Kee Park,
Chae-Yong Kim,
Sun Ha Paek,
Hee-Won Jung
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Predicting Pneumonitis Risk: A Dosimetric Alternative to Mean Lung Dose
DOI: 10.1016/j.ijrobp.2012.03.052
Purpose: To determine whether the association between mean lung dose (MLD) and risk of severe (grade ≥3) radiation pneumonitis (RP) depends on the dose distribution pattern to normal lung among patien...
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Susan L. Tucker,
Radhe Mohan,
Raweewan Liengsawangwong,
Mary K. Martel,
Zhongxing Liao
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Insufficiency Fractures After Pelvic Radiation Therapy for Uterine Cervical Cancer: An Analysis of Subjects in a Prospective Multi-institutional Trial, and Cooperative Study of the Japan Radiation Oncology Group (JAROG) and Japanese Radiation Oncology Study Group (JROSG)
DOI: 10.1016/j.ijrobp.2012.03.042
Purpose: To investigate pelvic insufficiency fractures (IF) after definitive pelvic radiation therapy for early-stage uterine cervical cancer, by analyzing subjects of a prospective, multi-institution...
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Sunao Tokumaru,
Takafumi Toita,
Masahiko Oguchi,
Tatsuya Ohno,
Shingo Kato,
Yuzuru Niibe,
Tomoko Kazumoto,
Takeshi Kodaira,
Masaaki Kataoka,
Naoto Shikama,
Masahiro Kenjo,
Chikako Yamauchi,
Osamu Suzuki,
Hideyuki Sakurai,
Teruki Teshima,
Yoshikazu Kagami,
Takashi Nakano,
Masahiro Hiraoka,
Norio Mitsuhashi,
Sho Kudo
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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A System for Continual Quality Improvement of Normal Tissue Delineation for Radiation Therapy Treatment Planning
DOI: 10.1016/j.ijrobp.2012.02.003
Purpose: To implement the “plan-do-check-act” (PDCA) cycle for the continual quality improvement of normal tissue contours used for radiation therapy treatment planning. Methods and Materials: The CT ...
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Jennifer Breunig,
Sophy Hernandez,
Jeffrey Lin,
Stacy Alsager,
Christine Dumstorf,
Jennifer Price,
Jennifer Steber,
Richard Garza,
Suneel Nagda,
Edward Melian,
Bahman Emami,
John C. Roeske
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Regional Normal Lung Tissue Density Changes in Patients Treated With Stereotactic Body Radiation Therapy for Lung Tumors
DOI: 10.1016/j.ijrobp.2011.11.080
Purpose: To describe regional lung tissue density changes in normal lung tissue of patients with primary and metastatic lung tumors who received stereotactic body radiation therapy (SBRT). Methods and...
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Quentin Diot,
Brian Kavanagh,
Tracey Schefter,
Laurie Gaspar,
Kelly Stuhr,
Moyed Miften
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Normal Tissue Anatomy for Oropharyngeal Cancer: Contouring Variability and Its Impact on Optimization
DOI: 10.1016/j.ijrobp.2012.03.031
Purpose: To evaluate the variability of organ at risk (OAR) delineation and the resulting impact on intensity modulated radiation therapy (IMRT) treatment plan optimization in head-and-neck cancer. Me...
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Mary Feng,
Candan Demiroz,
Karen A. Vineberg,
Avraham Eisbruch,
James M. Balter
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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Inhibition of Protease-activated Receptor 1 Ameliorates Intestinal Radiation Mucositis in a Preclinical Rat Model
DOI: 10.1016/j.ijrobp.2012.02.007
Purpose: To determine, using a specific small-molecule inhibitor of protease-activated receptor 1 (PAR1) signaling, whether the beneficial effect of thrombin inhibition on radiation enteropathy develo...
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Junru Wang,
Ashwini Kulkarni,
Madhu Chintala,
Louis M. Fink,
Martin Hauer-Jensen
et al.
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Full-length article
(In Press Corrected Proof)
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14 May 2012 |
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106Ruthenium Plaque Therapy (RPT) for Retinoblastoma
DOI: 10.1016/j.ijrobp.2011.11.002
Purpose: To evaluate the effectiveness of episcleral 106ruthenium plaque therapy (RPT) in the management of retinoblastoma. Methods and Materials: One hundred one RPTs were retrospectively analyzed th...
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Naoya Murakami,
Shigenobu Suzuki,
Yoshinori Ito,
Ryoichi Yoshimura,
Koji Inaba,
Yuki Kuroda,
Madoka Morota,
Hiroshi Mayahara,
Mototake Sakudo,
Akihisa Wakita,
Hiroyuki Okamoto,
Minako Sumi,
Yoshikazu Kagami,
Keiichi Nakagawa,
Kuni Ohtomo,
Jun Itami
et al.
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Full-length article
(In Press Corrected Proof)
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11 May 2012 |
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Contribution of 68Ga-DOTATOC PET/CT to Target Volume Delineation of Skull Base Meningiomas Treated With Stereotactic Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.03.021
Purpose: To investigate the potential impact of 68Ga-DOTATOC positron emission tomography (68Ga-DOTATOC-PET) in addition to magnetic resonance imaging (MRI) and computed tomography (CT) for retrospect...
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Reinhold Graf,
Fonyuy Nyuyki,
Ingo G. Steffen,
Roger Michel,
Daniel Fahdt,
Peter Wust,
Winfried Brenner,
Volker Budach,
Reinhard Wurm,
Michail Plotkin
et al.
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Full-length article
(In Press Corrected Proof)
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11 May 2012 |
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Are We Ready for Positron Emission Tomography/Computed Tomography–based Target Volume Definition in Lymphoma Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.02.023
Fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) has become indispensable for the clinical management of lymphomas. With consistent evidence that it is ...
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Kheng-Wei Yeoh,
N. George Mikhaeel
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Review article
(In Press Corrected Proof)
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11 May 2012 |
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A New Model for Predicting Acute Mucosal Toxicity in Head-and-Neck Cancer Patients Undergoing Radiotherapy With Altered Schedules
DOI: 10.1016/j.ijrobp.2012.02.004
Purpose: One of the worst radiation-induced acute effects in treating head-and-neck (HN) cancer is grade 3 or higher acute (oral and pharyngeal) mucosal toxicity (AMT), caused by the killing/depletion...
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Lidia Strigari,
Piernicola Pedicini,
Marco D’Andrea,
Paola Pinnarò,
Laura Marucci,
Carolina Giordano,
Marcello Benassi
et al.
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Full-length article
(In Press Corrected Proof)
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11 May 2012 |
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Prognostic Value of Molecular Subtypes, Ki67 Expression and Impact of Postmastectomy Radiation Therapy in Breast Cancer Patients With Negative Lymph Nodes After Mastectomy
DOI: 10.1016/j.ijrobp.2012.02.047
Purpose: To determine whether Ki67 expression and breast cancer subtypes could predict locoregional recurrence (LRR) and influence the postmastectomy radiotherapy (PMRT) decision in breast cancer (BC)...
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Jessica Selz,
Denise Stevens,
Ludivine Jouanneau,
Alain Labib,
Romuald Le Scodan
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Conformal Postoperative Radiotherapy in Patients With Positive Resection Margins and/or pT3-4 Prostate Adenocarcinoma
DOI: 10.1016/j.ijrobp.2012.04.002
Purpose: To evaluate outcome and toxicity of high-dose conformal radiotherapy (RT) after radical prostatectomy. Methods and Materials: Between August 1998 and December 2007, 182 consecutive patients w...
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Rita Bellavita,
Michela Massetti,
Iosief Abraha,
Marco Lupattelli,
Luigi Mearini,
Lorenzo Falcinelli,
Alessia Farneti,
Isabella Palumbo,
Massimo Porena,
Cynthia Aristei
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.03.030
Purpose: We used the Female Sexual Function Index (FSFI) to investigate the prevalence of sexual dysfunction (SD) and factors associated with diminished sexual functioning in early stage endometrial c...
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Shari Damast,
Kaled M. Alektiar,
Shari Goldfarb,
Anne Eaton,
Sujata Patil,
Jeffrey Mosenkis,
Antonia Bennett,
Thomas Atkinson,
Elizabeth Jewell,
Mario Leitao,
Richard Barakat,
Jeanne Carter,
Ethan Basch
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Eliminating Inconsistencies in Simulation and Treatment Planning Orders in Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.03.023
Purpose: To identify deficiencies with simulation and treatment planning orders and to develop corrective measures to improve safety and quality. Methods and Materials: At Washington University, the D...
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Lakshmi Santanam,
Ryan S. Brame,
Andrew Lindsey,
Todd Dewees,
Jon Danieley,
Jason Labrash,
Parag Parikh,
Jeffrey Bradley,
Imran Zoberi,
Jeff Michalski,
Sasa Mutic
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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A Multiphase Validation of Atlas-Based Automatic and Semiautomatic Segmentation Strategies for Prostate MRI
DOI: 10.1016/j.ijrobp.2011.07.046
Purpose: To perform a rigorous technological assessment and statistical validation of a software technology for anatomic delineations of the prostate on MRI datasets. Methods and Materials: A 3-phase ...
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Spencer Martin,
George Rodrigues,
Nikhilesh Patil,
Glenn Bauman,
David D'Souza,
Tracy Sexton,
David Palma,
Alexander V. Louie,
Farzad Khalvati,
Hamid R. Tizhoosh,
Stewart Gaede
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Positron Emission Tomography for Assessing Local Failure After Stereotactic Body Radiotherapy for Non-Small-Cell Lung Cancer
DOI: 10.1016/j.ijrobp.2011.10.035
Purpose: We analyzed whether positron emission tomography (PET)/computed tomography standardized uptake values (SUVs) after stereotactic body radiotherapy (SBRT) could predict local recurrence (LR) in...
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Xu Zhang,
Hui Liu,
Peter Balter,
Pamela K. Allen,
Ritsuko Komaki,
Tinsu Pan,
Hubert H. Chuang,
Joe Y. Chang
et al.
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Full-length article
(In Press Corrected Proof)
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08 May 2012 |
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Esophageal Toxicity From High-Dose, Single-Fraction Paraspinal Stereotactic Radiosurgery
DOI: 10.1016/j.ijrobp.2012.01.080
Purpose: To report the esophageal toxicity from single-fraction paraspinal stereotactic radiosurgery (SRS) and identify dosimetric and clinical risk factors for toxicity. Methods and Materials: A tota...
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Brett W. Cox,
Andrew Jackson,
Margie Hunt,
Mark Bilsky,
Yoshiya Yamada
et al.
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Full-length article
(In Press Corrected Proof)
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08 May 2012 |
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The Use of Photon Beams of a Flattening Filter-free Linear Accelerator for Hypofractionated Volumetric Modulated Arc Therapy in Localized Prostate Cancer
DOI: 10.1016/j.ijrobp.2011.10.019
Purpose: To evaluate the potential usage of flattening filter-free (FFF) photon beams in the treatment of prostate cancer. Methods and Materials: Volumetric-modulated arc therapy (VMAT) treatment plan...
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Daniel R. Zwahlen,
Stephanie Lang,
Jan Hrbacek,
Christoph Glanzmann,
Stephan Kloeck,
Yousef Najafi,
Tino Streller,
Gabriela Studer,
Kathrin Zaugg,
Urs M. Luetolf
et al.
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Full-length article
(In Press Corrected Proof)
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08 May 2012 |
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The Abscopal Effect Associated With a Systemic Anti-melanoma Immune Response
DOI: 10.1016/j.ijrobp.2012.03.017
The clearance of nonirradiated tumors after localized radiation therapy is known as the abscopal effect. Activation of an antitumor immune response has been proposed as a mechanism for the abscopal ef...
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Emily F. Stamell,
Jedd D. Wolchok,
Sacha Gnjatic,
Nancy Y. Lee,
Isaac Brownell
et al.
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Short communication
(In Press Corrected Proof)
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07 May 2012 |
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Fractionated Stereotactic Radiotherapy of Vestibular Schwannomas Accelerates Hearing Loss
DOI: 10.1016/j.ijrobp.2012.01.078
Objective: To evaluate long-term tumor control and hearing preservation rates in patients with vestibular schwannoma treated with fractionated stereotactic radiotherapy (FSRT), comparing hearing prese...
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Rune Rasmussen,
Magnus Claesson,
Sven-Eric Stangerup,
Henrik Roed,
Ib Jarle Christensen,
Per Cayé-Thomasen,
Marianne Juhler
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Evaluation of Tumor Shape Variability in Head-and-Neck Cancer Patients Over the Course of Radiation Therapy Using Implanted Gold Markers
DOI: 10.1016/j.ijrobp.2012.03.014
Purpose: This study quantifies tumor shape variability in head-and-neck cancer patients during radiation therapy using implanted markers. Methods and Materials: Twenty-seven patients with oropharyngea...
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Olga Hamming-Vrieze,
Simon Robert van Kranen,
Suzanne van Beek,
Wilma Heemsbergen,
Marcel van Herk,
Michiel Wilhelmus Maria van den Brekel,
Jan-Jakob Sonke,
Coenraad Robert Nico Rasch
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Quantifying the Impact of Immediate Reconstruction in Postmastectomy Radiation: A Large, Dose-Volume Histogram-Based Analysis
DOI: 10.1016/j.ijrobp.2012.03.026
Purpose: To assess the impact of immediate breast reconstruction on postmastectomy radiation (PMRT) using dose-volume histogram (DVH) data. Methods and Materials: Two hundred forty-seven women underwe...
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Nisha Ohri,
Peter G. Cordeiro,
Jennifer Keam,
Ase Ballangrud,
Weiji Shi,
Zhigang Zhang,
Claire T. Nerbun,
Katherine M. Woch,
Nicholas F. Stein,
Ying Zhou,
Beryl McCormick,
Simon N. Powell,
Alice Y. Ho
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Cosmetic Outcome and Seroma Formation After Breast-Conserving Surgery With Intraoperative Radiation Therapy Boost for Early Breast Cancer
DOI: 10.1016/j.ijrobp.2012.03.015
Purpose: To evaluate cosmetic outcome and its association with breast wound seroma after breast-conserving surgery (BCS) with targeted intraoperative radiation therapy (tIORT) boost for early breast c...
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Sashendra Senthi,
Emma Link,
Boon H. Chua
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Using Generalized Equivalent Uniform Dose Atlases to Combine and Analyze Prospective Dosimetric and Radiation Pneumonitis Data From 2 Non-Small Cell Lung Cancer Dose Escalation Protocols
DOI: 10.1016/j.ijrobp.2012.03.024
Purpose: To demonstrate the use of generalized equivalent uniform dose (gEUD) atlas for data pooling in radiation pneumonitis (RP) modeling, to determine the dependence of RP on gEUD, to study the con...
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Fan Liu,
Ellen D. Yorke,
José S.A. Belderbos,
Gerben R. Borst,
Kenneth E. Rosenzweig,
Joos V. Lebesque,
Andrew Jackson
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Long-Term Results Following Postoperative Radiotherapy for Soft Tissue Sarcomas of the Extremity
DOI: 10.1016/j.ijrobp.2012.01.074
Purpose: To review long-term outcomes following postoperative radiotherapy (RT) for extremity soft tissue sarcoma (STS) and identify variables affecting the therapeutic ratio. Methods and Materials: B...
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Lisa McGee,
Daniel J. Indelicato,
Roi Dagan,
Christopher G. Morris,
Jacquelyn A. Knapik,
John D. Reith,
Mark T. Scarborough,
C. Parker Gibbs,
Robert B. Marcus,
Robert A. Zlotecki
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Phase II Study of Accelerated High-Dose Radiotherapy With Concurrent Chemotherapy for Patients With Limited Small-Cell Lung Cancer: Radiation Therapy Oncology Group Protocol 0239
DOI: 10.1016/j.ijrobp.2012.01.075
Purpose: To investigate whether high-dose thoracic radiation given twice daily during cisplatin-etoposide chemotherapy for limited small-cell lung cancer (LSCLC) improves survival, acute esophagitis, ...
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Ritsuko Komaki,
Rebecca Paulus,
David S. Ettinger,
Gregory M.M. Videtic,
Jeffrey D. Bradley,
Bonnie S. Glisson,
Corey J. Langer,
William T. Sause,
Walter J. Curran,
Hak Choy
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Cone Beam Computed Tomography Image Guidance System for a Dedicated Intracranial Radiosurgery Treatment Unit
DOI: 10.1016/j.ijrobp.2012.03.022
Purpose: Image guidance has improved the precision of fractionated radiation treatment delivery on linear accelerators. Precise radiation delivery is particularly critical when high doses are delivere...
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Mark Ruschin,
Philip T. Komljenovic,
Steve Ansell,
Cynthia Ménard,
Gregory Bootsma,
Young-Bin Cho,
Caroline Chung,
David Jaffray
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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How Radiation Oncologists Would Disclose Errors: Results of a Survey of Radiation Oncologists and Trainees
DOI: 10.1016/j.ijrobp.2012.03.010
Purpose: To analyze error disclosure attitudes of radiation oncologists and to correlate error disclosure beliefs with survey-assessed disclosure behavior. Methods and Materials: With institutional re...
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Suzanne B. Evans,
James B. Yu,
Anees Chagpar
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Impact of Postmastectomy Radiation on Locoregional Recurrence in Breast Cancer Patients With 1-3 Positive Lymph Nodes Treated With Modern Systemic Therapy
DOI: 10.1016/j.ijrobp.2012.01.076
Purpose: Postmastectomy radiation therapy (PMRT) remains controversial for patients with 1-3 positive lymph nodes (LN+). Methods and Materials: We conducted a retrospective review of all 369 breast ca...
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Rahul D. Tendulkar,
Sana Rehman,
Monica E. Shukla,
Chandana A. Reddy,
Halle Moore,
G. Thomas Budd,
Jill Dietz,
Joseph P. Crowe,
Roger Macklis
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Acute Esophagus Toxicity in Lung Cancer Patients After Intensity Modulated Radiation Therapy and Concurrent Chemotherapy
DOI: 10.1016/j.ijrobp.2012.03.027
Purpose: The purpose of this study was to investigate the dose-effect relation between acute esophageal toxicity (AET) and the dose-volume parameters of the esophagus after intensity modulated radiati...
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Margriet Kwint,
Wilma Uyterlinde,
Jasper Nijkamp,
Chun Chen,
Josien de Bois,
Jan-Jakob Sonke,
Michel van den Heuvel,
Joost Knegjens,
Marcel van Herk,
José Belderbos
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Positron Emission Tomography (PET) Evaluation After Initial Chemotherapy and Radiation Therapy Predicts Local Control in Rhabdomyosarcoma
DOI: 10.1016/j.ijrobp.2012.01.077
Purpose: 18-fluorodeoxyglucose positron emission tomography (PET) is already an integral part of staging in rhabdomyosarcoma. We investigated whether primary-site treatment response characterized by s...
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Kavita V. Dharmarajan,
Leonard H. Wexler,
Somali Gavane,
Josef J. Fox,
Heiko Schoder,
Ashlyn K. Tom,
Alison N. Price,
Paul A. Meyers,
Suzanne L. Wolden
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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Success Breeds Success: Authorship Distribution in the Red Journal, 1975-2011
DOI: 10.1016/j.ijrobp.2012.03.012
Purpose: Publication analysis has value in evaluating the mechanics of academic efforts in specific scientific communities. The specific aim of this study was to evaluate whether established bibliomet...
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Emma Holliday,
Clifton David Fuller,
Lynn D. Wilson,
Charles R. Thomas
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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The Dosimetric Impact of Prostate Rotations During Electromagnetically Guided External-Beam Radiation Therapy
DOI: 10.1016/j.ijrobp.2012.03.020
Purpose: To study the impact of daily rotations and translations of the prostate on dosimetric coverage during radiation therapy (RT). Methods and Materials: Real-time tracking data for 26 patients we...
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Hanan Amro,
Daniel A. Hamstra,
Daniel L. Mcshan,
Howard Sandler,
Karen Vineberg,
Scott Hadley,
Dale Litzenberg
et al.
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Full-length article
(In Press Corrected Proof)
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03 May 2012 |
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Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images
DOI: 10.1016/j.ijrobp.2012.03.006
Purpose: To verify the geometric accuracy of gated RapidArc treatment using kV images acquired during dose delivery. Methods and Materials: Twenty patients were treated using the gated RapidArc techni...
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Ruijiang Li,
Edward Mok,
Daniel T. Chang,
Megan Daly,
Billy W. Loo,
Maximilian Diehn,
Quynh-Thu Le,
Albert Koong,
Lei Xing
et al.
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Full-length article
(In Press Corrected Proof)
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03 May 2012 |
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Implementation of Remote 3-Dimensional Image Guided Radiation Therapy Quality Assurance for Radiation Therapy Oncology Group Clinical Trials
DOI: 10.1016/j.ijrobp.2012.03.002
Purpose: To report the process and initial experience of remote credentialing of three-dimensional (3D) image guided radiation therapy (IGRT) as part of the quality assurance (QA) of submitted data fo...
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Yunfeng Cui,
James M. Galvin,
William Parker,
Stephen Breen,
Fang-Fang Yin,
Jing Cai,
Lech S. Papiez,
X. Allen Li,
Greg Bednarz,
Wenzhou Chen,
Ying Xiao
et al.
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Full-length article
(In Press Corrected Proof)
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30 April 2012 |