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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Divergent effects of a CLA-enriched beef diet on metabolic health in ApoE−/− and ob/ob mice
DOI: 10.1016/j.jnutbio.2011.12.006
Abstract: Conjugated linoleic acid (CLA) is found naturally in meat and dairy products, and represents a potential therapeutic functional nutrient. However, given the discrepancies in isomer compositi...
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Clare M. Reynolds,
Sinead Toomey,
Rachael McBride,
Jolene McMonagle,
Melissa J. Morine,
Orina Belton,
Aidan P. Moloney,
Helen M. Roche
et al.
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Full-length article
(In Press Corrected Proof)
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24 May 2012 |
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Plasma total antioxidant capacity is associated with dietary intake and plasma level of antioxidants in postmenopausal women
DOI: 10.1016/j.jnutbio.2011.12.004
Abstract: Increased plasma total antioxidant capacity (TAC) has been associated with a high consumption of fruits and vegetables. However, limited information is available on whether plasma TAC reflec...
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Ying Wang,
Meng Yang,
Sang-Gil Lee,
Catherine G. Davis,
Anne Kenny,
Sung I. Koo,
Ock K. Chun
et al.
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Full-length article
(In Press Corrected Proof)
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23 May 2012 |
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Postprandial blood cell transcriptomics in response to the ingestion of dairy products by healthy individuals
DOI: 10.1016/j.jnutbio.2012.01.001
Abstract: The aim of this intervention study was to measure genome-wide postprandial gene expression in human blood cells after the ingestion of a single serving of milk, to identify the downstream ph...
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Francina M. Sagaya,
Richard F. Hurrell,
Guy Vergères
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Caveolin-3 is involved in the protection of resveratrol against high-fat-diet-induced insulin resistance by promoting GLUT4 translocation to the plasma membrane in skeletal muscle of ovariectomized rats
DOI: 10.1016/j.jnutbio.2011.12.003
Abstract: Insulin resistance is recognized as a common metabolic factor which predicts the future development of both type 2 diabetes and atherosclerotic disease. Resveratrol (RSV), an agonist of estr...
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Zhi Tan,
Li-Jun Zhou,
Pan-Wei Mu,
Shui-Ping Liu,
Si-Juan Chen,
Xiao-Dong Fu,
Ting-Huai Wang
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice
DOI: 10.1016/j.jnutbio.2011.12.005
Abstract: Indole-3-carbinol (I3C) is a compound found in high concentrations in Brassica family vegetables, including broccoli, cauliflower and cabbage, and is regarded as a promising chemopreventive ...
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Youngshim Choi,
Yunjung Kim,
Soyoung Park,
Ki Won Lee,
Taesun Park
et al.
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Full-length article
(In Press Corrected Proof)
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09 May 2012 |
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Osteocalcin and vitamin D status are inversely associated with homeostatic model assessment of insulin resistance in Canadian Aboriginal and white women: the First Nations Bone Health Study
DOI: 10.1016/j.jnutbio.2011.12.007
Abstract: Objective: Osteocalcin, a protein synthesized by osteoblasts, and vitamin D status have independently been implicated in energy metabolism and glucose regulation. This study was conducted to...
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Hope A. Weiler,
Julie Lowe,
John Krahn,
William D. Leslie
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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The iron regulatory hormone hepcidin inhibits expression of iron release as well as iron uptake proteins in J774 cells
DOI: 10.1016/j.jnutbio.2011.12.002
Abstract: The mechanism by which hepcidin controls cellular iron release protein ferroportin 1 (Fpn1) in macrophages has been well established. However, little is known about the effects of hepcidin o...
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Fang Du,
Zhong-ming Qian,
Qi Gong,
Zhou Jin Zhu,
Lina Lu,
Ya Ke
et al.
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Full-length article
(In Press Corrected Proof)
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07 May 2012 |
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n-3 and n-6 polyunsaturated fatty acids differentially regulate adipose angiotensinogen and other inflammatory adipokines in part via NF-κB-dependent mechanisms
DOI: 10.1016/j.jnutbio.2011.11.009
Abstract: Excessive secretion of proinflammatory adipokines has been linked to metabolic disorders. We have previously documented anti-inflammatory effects of n-3 polyunsaturated fatty acids (n-3 PUFA...
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Nalin Siriwardhana,
Nishan S. Kalupahana,
Sarah Fletcher,
Wenting Xin,
Kate J. Claycombe,
Annie Quignard-Boulange,
Ling Zhao,
Arnold M. Saxton,
Naima Moustaid-Moussa
et al.
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Full-length article
(In Press Corrected Proof)
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05 April 2012 |
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The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells
DOI: 10.1016/j.jnutbio.2011.11.010
Abstract: Vitamin K (VK) has diverse protective effects against osteoporosis, atherosclerosis and carcinogenesis. We recently reported that menatetrenone, a VK2 analogue, suppressed nuclear factor (NF...
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JingHe Xia,
Sachiko Matsuhashi,
Hiroshi Hamajima,
Shinji Iwane,
Hirokazu Takahashi,
Yuichiro Eguchi,
Toshihiko Mizuta,
Kazuma Fujimoto,
Shun'ichi Kuroda,
Iwata Ozaki
et al.
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Full-length article
(In Press Corrected Proof)
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04 April 2012 |
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Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function
DOI: 10.1016/j.jnutbio.2011.11.011
Abstract: Nonalcoholic steatosis is an important hepatic complication of obesity linked to mitochondrial dysfunction and insulin resistance. Furthermore, lipoic acid has been reported to have benefici...
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M. Pilar Valdecantos,
Patricia Pérez-Matute,
Pedro González-Muniesa,
Pedro L. Prieto-Hontoria,
María J. Moreno-Aliaga,
J. Alfredo Martínez
et al.
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Full-length article
(In Press Corrected Proof)
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30 March 2012 |
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TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice
DOI: 10.1016/j.jnutbio.2011.12.001
Abstract: Aims/hypothesis: Inflammation and ectopic lipid deposition contribute to obesity-related insulin resistance (IR). Studies have shown that deficiency of the proinflammatory cytokine tumor nec...
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Jérôme Salles,
Nicolas Tardif,
Jean-François Landrier,
Isabelle Mothe-Satney,
Christelle Guillet,
Carole Boue-Vaysse,
Lydie Combaret,
Christophe Giraudet,
Véronique Patrac,
Justine Bertrand-Michel,
Philippe Denis,
Jean-Michel Chardigny,
Yves Boirie,
Stéphane Walrand
et al.
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Full-length article
(In Press Corrected Proof)
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30 March 2012 |
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Maternal green tea extract supplementation to rats fed a high-fat diet ameliorates insulin resistance in adult male offspring
DOI: 10.1016/j.jnutbio.2011.11.008
Abstract: Maternal overnutrition is associated with increased risk of metabolic disorders in the offspring. This study tested the hypothesis that maternal green tea (GT) supplementation can alleviate ...
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Shiying Li,
Iris M.Y. Tse,
Edmund T.S. Li
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Full-length article
(In Press Corrected Proof)
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30 March 2012 |
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Sulforaphane inhibits pancreatic cancer through disrupting Hsp90–p50Cdc37 complex and direct interactions with amino acids residues of Hsp90
DOI: 10.1016/j.jnutbio.2011.11.004
Abstract: Sulforaphane [1-isothiocyanato-4-(methyl-sulfinyl) butane)], an isothiocyanate derived from cruciferous vegetables, has been shown to possess potent chemopreventive activity. We analyzed the...
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Yanyan Li,
G. Elif Karagöz,
Young Ho Seo,
Tao Zhang,
Yiqun Jiang,
Yanke Yu,
Afonso M.S. Duarte,
Steven J. Schwartz,
Rolf Boelens,
Kate Carroll,
Stefan G.D. Rüdiger,
Duxin Sun
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption
DOI: 10.1016/j.jnutbio.2011.10.013
Abstract: Obesity is often associated with disorders of iron homeostasis; however, the underlying mechanisms are not fully understood. Hepcidin is a key regulator of iron metabolism and may be respons...
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Thomas Sonnweber,
Claudia Ress,
Manfred Nairz,
Igor Theurl,
Andrea Schroll,
Anthony T. Murphy,
Victor Wroblewski,
Derrick R. Witcher,
Patrizia Moser,
Christoph F. Ebenbichler,
Susanne Kaser,
Günter Weiss
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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Dairy fat blends high in α-linolenic acid are superior to n-3 fatty-acid-enriched palm oil blends for increasing DHA levels in the brains of young rats
DOI: 10.1016/j.jnutbio.2011.10.011
Abstract: Achieving an appropriate docosahexaenoic acid (DHA) status in the neonatal brain is an important goal of neonatal nutrition. We evaluated how different dietary fat matrices improved DHA cont...
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Qin Du,
Jean-Charles Martin,
Genevieve Agnani,
Nicole Pages,
Pascale Leruyet,
Pierre Carayon,
Bernadette Delplanque
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity
DOI: 10.1016/j.jnutbio.2011.10.012
Abstract: α-Tocopheryl succinate (α-TOS) inhibits oxidative phosphorylation at the level of mitochondrial complex I and II, thus promoting cancer cell death through mitochondrial reactive oxygen speci...
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Ilaria Bellezza,
Arianna Tucci,
Francesco Galli,
Silvia Grottelli,
Anna Lisa Mierla,
Francesca Pilolli,
Alba Minelli
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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Impaired insulin and leptin sensitivity in the offspring of moderate caloric-restricted dams during gestation is early programmed
DOI: 10.1016/j.jnutbio.2011.11.005
Abstract: We aimed to assess the mechanisms responsible for hyperphagia and metabolic alterations caused by maternal moderate caloric restriction during gestation. Male and female offspring of control...
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Mariona Palou,
Jadwiga Konieczna,
Juana María Torrens,
Juana Sánchez,
Teresa Priego,
Maria Luiza Fernandes,
Andreu Palou,
Catalina Picó
et al.
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Full-length article
(In Press Corrected Proof)
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26 March 2012 |
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Modulation of immune cell proliferation and chemotaxis towards CC chemokine ligand (CCL)-21 and CXC chemokine ligand (CXCL)-12 in undenatured whey protein-treated mice
DOI: 10.1016/j.jnutbio.2011.11.006
Abstract: Whey protein concentrates (WPCs) enhance innate mucosal immunity during early life and have a protective role in some immune disorders. To further elucidate the potential benefits of this pr...
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Gamal Badr,
Hossam Ebaid,
Mohamed Mohany,
Abdelaziz Saber Abuelsaad
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Procyanidins modify insulinemia by affecting insulin production and degradation
DOI: 10.1016/j.jnutbio.2011.10.010
Abstract: Previous studies from our research group have suggested that procyanidins modify glycemia and insulinemia. The aim of this work was to evaluate the effects of procyanidins on β-cell function...
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Anna Castell-Auví,
Lídia Cedó,
Victor Pallarès,
M. Teresa Blay,
Montserrat Pinent,
M. José Motilva,
Santiago Garcia-Vallvé,
Gerard Pujadas,
Pierre Maechler,
Anna Ardévol
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Docosahexaenoic acid suppresses the expression of FoxO and its target genes
DOI: 10.1016/j.jnutbio.2011.11.003
Abstract: Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid, has previously been shown to ameliorate obesity-associated metabolic syndrome. To decipher the mechanism responsible for the be...
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Yu-Jen Chen,
Chih-Chien Chen,
Tsai-Kun Li,
Pei-Hwa Wang,
Li-Ru Liu,
Fang-Ying Chang,
Ya-Chin Wang,
Yu-Hsiang Yu,
Shau-Ping Lin,
Harry J. Mersmann,
Shih-Torng Ding
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7α1 in the liver of weaning piglets
DOI: 10.1016/j.jnutbio.2011.11.007
Abstract: To investigate the effect of maternal dietary protein on hepatic cholesterol metabolism in offspring pigs and to detect underlying epigenetic mechanisms, 14 primiparous purebred Meishan sows...
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Rihua Cong,
Yimin Jia,
Runsheng Li,
Yingdong Ni,
Xiaojing Yang,
Qinwei Sun,
Nahid Parvizi,
Ruqian Zhao
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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Influence of long-term caloric restriction on myocardial and cardiomyocyte contractile function and autophagy in mice
DOI: 10.1016/j.jnutbio.2011.11.002
Abstract: Both clinical and experimental evidence has revealed that calorie restriction (CR) is capable of improving heart function. However, most the reports are focused on the effect of CR on the pa...
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Xuefeng Han,
Subat Turdi,
Nan Hu,
Rui Guo,
Yingmei Zhang,
Jun Ren
et al.
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Full-length article
(In Press Corrected Proof)
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23 March 2012 |
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MicroRNAs in the growth plate are responsive to nutritional cues: association between miR-140 and SIRT1
DOI: 10.1016/j.jnutbio.2011.09.010
Abstract: MicroRNAs (miRNAs) have been reported to be involved in a variety of functions, including skeletal development and longitudinal growth. The aim of this study was to investigate the role of m...
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Rakefet Pando,
Naomi Even-Zohar,
Biana Shtaif,
Liat Edry,
Noam Shomron,
Moshe Phillip,
Galia Gat-Yablonski
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Comparison of high-protein diets and leucine supplementation in the prevention of metabolic syndrome and related disorders in mice
DOI: 10.1016/j.jnutbio.2011.10.005
Abstract: High-protein diets have been shown to promote weight loss, to improve glucose homeostasis and to increase energy expenditure and fat oxidation. We aimed to study whether leucine supplementat...
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Anne Freudenberg,
Klaus J. Petzke,
Susanne Klaus
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis
DOI: 10.1016/j.jnutbio.2011.10.007
Abstract: It has been demonstrated in various animal models that the oral administration of green tea (GT) extracts in drinking water can inhibit tumor growth, but the effects of brewed GT on factors ...
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Susanne M. Henning,
Piwen Wang,
Jonathan Said,
Clara Magyar,
Brandon Castor,
Ngan Doan,
Carmen Tosity,
Aune Moro,
Kun Gao,
Luyi Li,
David Heber
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Sesamol alleviates diet-induced cardiometabolic syndrome in rats via up-regulating PPARγ, PPARα and e-NOS
DOI: 10.1016/j.jnutbio.2011.09.011
Abstract: Increased oxidative stress and inflammation in obesity are the central and causal components in the pathogenesis and progression of cardiometabolic syndrome (CMetS). The aim of the study was...
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Ashok Kumar Sharma,
Saurabh Bharti,
Jagriti Bhatia,
Saroj Nepal,
Salma Malik,
Ruma Ray,
Santosh Kumari,
Dharamvir Singh Arya
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Curcumin reduces the cardiac ischemia–reperfusion injury: involvement of the toll-like receptor 2 in cardiomyocytes
DOI: 10.1016/j.jnutbio.2011.10.004
Abstract: Curcumin, a polyphenolic compound derived from turmeric, has protective effects on myocardial injury through attenuation of oxidative stress and inflammation. Toll-like receptor 2 (TLR2), a ...
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Yong Sook Kim,
Jin Sook Kwon,
Young Kuk Cho,
Myung Ho Jeong,
Jeong Gwan Cho,
Jong Chun Park,
Jung Chaee Kang,
Youngkeun Ahn
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Investigation of the molecular response to folate metabolism inhibition
DOI: 10.1016/j.jnutbio.2011.10.006
Abstract: We investigated the molecular response to folate metabolism inhibition by exposing human lymphoblast cell lines to the methionine adenosyltransferase inhibitor cycloleucine. We carried out m...
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Nicola Carroll,
Linda Hughes,
Gráinne McEntee,
Anne Parle-McDermott
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Thiacremonone, a sulfur compound isolated from garlic, attenuates lipid accumulation partially mediated via AMPK activation in 3T3-L1 adipocytes
DOI: 10.1016/j.jnutbio.2011.10.008
Abstract: Garlic extracts exert anti-cancer and anti-inflammatory effects. However, the anti-adipogenic effect of garlic-derived compounds remains unclear. In this study, we examined the effect of thi...
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Eun Jin Kim,
Dong Hun Lee,
Hee Jong Kim,
So Jung Lee,
Jung Ok Ban,
Min Chul Cho,
Heon Sang Jeong,
Young Yang,
Jin Tae Hong,
Do Young Yoon
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice
DOI: 10.1016/j.jnutbio.2011.10.003
Abstract: Polyamines play a critical role in the development of intestinal and immune systems during the infant breastfeeding period, but the effect of polyamines on the microbiota has not been report...
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Carlos Gómez-Gallego,
María C. Collado,
Toni Ilo,
Ulla-Marjut Jaakkola,
María J. Bernal,
María J. Periago,
Seppo Salminen,
Gaspar Ros,
Rafael Frias
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Perinatal undernutrition alters intestinal alkaline phosphatase and its main transcription factors KLF4 and Cdx1 in adult offspring fed a high-fat diet
DOI: 10.1016/j.jnutbio.2011.10.001
Abstract: Nutrient restriction during gestation and/or suckling is associated with an increased risk of developing inflammation, obesity and metabolic diseases in adulthood. However, the underlying me...
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Jean-Paul Lallès,
Ricardo Orozco-Solís,
Francisco Bolaños-Jiménez,
Pierre de Coppet,
Gwénola Le Dréan,
Jean-Pierre Segain
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Disturbed zinc homeostasis in diabetic patients by in vitro and in vivo analysis of insulinomimetic activity of zinc
DOI: 10.1016/j.jnutbio.2011.09.008
Abstract: Disturbances of zinc homeostasis have been observed in several diseases, including diabetes mellitus. To further characterize the association between zinc and diabetes, we recruited 75 patie...
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Judith Jansen,
Eva Rosenkranz,
Silke Overbeck,
Sabine Warmuth,
Eugenio Mocchegiani,
Robertina Giacconi,
Ralf Weiskirchen,
Wolfram Karges,
Lothar Rink
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Differential regulation of CD4+ T helper cell responses by curcumin in experimental autoimmune encephalomyelitis
DOI: 10.1016/j.jnutbio.2011.10.002
Abstract: Nutraceuticals and phytochemicals are important regulators of human health and diseases. Curcumin is a polyphenolic phytochemical isolated from the rhizome of the plant Curcuma longa (turmer...
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Saravanan Kanakasabai,
Eli Casalini,
Crystal C. Walline,
Caiqing Mo,
Wanida Chearwae,
John J. Bright
et al.
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Full-length article
(In Press Corrected Proof)
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09 March 2012 |
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Regulators of protein metabolism are affected by cyclical nutritional treatments with diets varying in protein and energy content
DOI: 10.1016/j.jnutbio.2011.09.009
Abstract: There is evidence that the E3 ubiquitin ligases muscle ring finger-1 (MuRF1) and atrogin-1, which mediate the ubiquitination of certain proteins and thereby their proteolysis, are regulated ...
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Sourour Boussaid-Om Ezzine,
Sonia Métayer-Coustard,
Anne Collin,
Nicole Rideau,
Christine Leterrier,
Isabelle Bouvarel,
Iban Seiliez,
Sophie Tesseraud
et al.
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Full-length article
(In Press Corrected Proof)
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03 February 2012 |
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PPARγ as a molecular target of EPA anti-inflammatory activity during TNF-α-impaired skeletal muscle cell differentiation
DOI: 10.1016/j.jnutbio.2011.09.005
Abstract: Activated skeletal muscle satellite cells facilitate muscle repair or growth through proliferation, differentiation and fusion into new or existing myotubes. Elevated levels of the proinflam...
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Peter Magee,
Stephen Pearson,
Jayde Whittingham-Dowd,
Jeremy Allen
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Full-length article
(In Press Corrected Proof)
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03 February 2012 |
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Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10
DOI: 10.1016/j.jnutbio.2011.09.004
Abstract: Uptake of docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) improves the treatment of cancer and reduces tumor-associated macrophage count. However, the mechanism of this relationship i...
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Ming-Hsun Wu,
Yo-Ting Tsai,
Kuo-Tai Hua,
Kun-Che Chang,
Min-Liang Kuo,
Ming-Tsan Lin
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms
DOI: 10.1016/j.jnutbio.2011.08.008
Abstract: Objective: Senescence of vascular cells contributes to the development of cardiovascular diseases and the overall aging. This study was undertaken to investigate the effects of resveratrol (...
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Yuhan Tang,
Jian Xu,
Wei Qu,
Xiaolin Peng,
Peng Xin,
Xuefeng Yang,
Chenjiang Ying,
Xiufa Sun,
Liping Hao
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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The soybean peptide aglycin regulates glucose homeostasis in type 2 diabetic mice via IR/IRS1 pathway
DOI: 10.1016/j.jnutbio.2011.09.007
Abstract: It has been previously reported that aglycin, a natural bioactive peptide isolated from soybean, is stable in digestive enzymes and has an antidiabetic potential. With a view to explore the ...
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Jingli Lu,
Ying Zeng,
Wenrui Hou,
Shasha Zhang,
Lulu Li,
Xiang Luo,
Wei Xi,
Zhengwang Chen,
Ming Xiang
et al.
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Full-length article
(In Press Corrected Proof)
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25 January 2012 |
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Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation
DOI: 10.1016/j.jnutbio.2011.09.003
Abstract: Oncoprotein-induced transcript 1 (Oit1) was previously identified as a dietary fat-induced gene in the small intestine of C57Bl/6J mice. In this study, we further characterized Oit1 and its ...
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Nicole J.W. de Wit,
Noortje IJssennagger,
Els Oosterink,
Shohreh Keshtkar,
Guido J.E.J. Hooiveld,
Ronald P. Mensink,
Sebastiaan Hammer,
Johannes W.A. Smit,
Michael Müller,
Roelof van der Meer
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Coffee polyphenol caffeic acid but not chlorogenic acid increases 5′AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle
DOI: 10.1016/j.jnutbio.2011.09.001
Abstract: Chlorogenic acid is an ester of caffeic and quinic acids, and is one of the most widely consumed polyphenols because it is abundant in foods, especially coffee. We explored whether chlorogen...
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Satoshi Tsuda,
Tatsuro Egawa,
Xiao Ma,
Rieko Oshima,
Eriko Kurogi,
Tatsuya Hayashi
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease
DOI: 10.1016/j.jnutbio.2011.07.012
Abstract: Oxidative stress and neuroinflammation are hallmarks of neurodegenerative diseases, which do not play independently but work synergistically through complex interactions exacerbating neurode...
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Sa Suk Kim,
Juhee Lim,
Yeojin Bang,
Jiyeong Gal,
Sang-Uk Lee,
Young-Chang Cho,
Goo Yoon,
Bok Yun Kang,
Seung Hoon Cheon,
Hyun Jin Choi
et al.
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Full-length article
(In Press Corrected Proof)
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09 January 2012 |
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Adipose tissue proteomes of intrauterine growth-restricted piglets artificially reared on a high-protein neonatal formula
DOI: 10.1016/j.jnutbio.2011.09.002
Abstract: The eventuality that adipose tissues adapt to neonatal nutrition in a way that may program later adiposity or obesity in adulthood is receiving increasing attention in neonatology. This stud...
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Ousseynou Sarr,
Isabelle Louveau,
Isabelle Le Huërou-Luron,
Florence Gondret
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Consumption of high-fat diet induces tumor progression and epithelial–mesenchymal transition of colorectal cancer in a mouse xenograft model
DOI: 10.1016/j.jnutbio.2011.07.011
Abstract: Epidemiologic studies suggest that intake of high-fat diet (HFD) promotes colon carcinogenesis. Epithelial–mesenchymal transition (EMT) and inflammation play important roles during tumor pro...
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Feng-Yao Tang,
Man-Hui Pai,
En-Pei Isabel Chiang
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Effects of physiological quercetin metabolites on interleukin-1β-induced inducible NOS expression
DOI: 10.1016/j.jnutbio.2011.08.007
Abstract: Cytokines released by inflammatory cells around the pancreatic islets are implicated in the pathogenesis of diabetes mellitus. Specifically, interleukin-1β (IL-1β) is known to be involved in...
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Jae Min Cho,
Seo-Yoon Chang,
Dong-Bin Kim,
Paul W. Needs,
Yang-Hyeok Jo,
Myung-Jun Kim
et al.
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Full-length article
(In Press Corrected Proof)
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06 January 2012 |
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Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes
DOI: 10.1016/j.jnutbio.2011.08.004
Abstract: Inflammation and hepatic stellate cell (HSC) activation are the most crucial steps in the formation of hepatic fibrosis. Hepatocytes damaged by viral or bacterial infection, alcohol or toxic...
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Mu-En Wang,
Yi-Chen Chen,
I-Shu Chen,
Shu-Chen Hsieh,
Sheng-Shih Chen,
Chih-Hsien Chiu
et al.
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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N-3 long-chain polyunsaturated fatty acids inhibit smooth muscle cell migration by modulating urokinase plasminogen activator receptor through MEK/ERK-dependent and -independent mechanisms
DOI: 10.1016/j.jnutbio.2011.08.005
Abstract: Smooth muscle cell (SMC) migration is a major and complex feature of atherosclerosis and restenosis. N-3 long-chain polyunsaturated fatty acids (LCPUFAs) affect SMC migration; however, the m...
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Claire Whyte,
Frank Thies,
Lise Peyrol,
Denis Balcerzak
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks
DOI: 10.1016/j.jnutbio.2011.08.006
Abstract: The 3-thia fatty acid tetradecylthioacetic acid (TTA) is a synthetic modified fatty acid, which, similar with dietary fish oil (FO), influences the regulation of lipid metabolism, the inflam...
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Natalya Filipchuk Vigerust,
Daniel Cacabelos,
Lena Burri,
Kjetil Berge,
Hege Wergedahl,
Bjørn Christensen,
Manuel Portero-Otin,
Asgaut Viste,
Reinald Pamplona,
Rolf Kristian Berge,
Bodil Bjørndal
et al.
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Full-length article
(In Press Corrected Proof)
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05 January 2012 |
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Soy peptide-induced stem cell proliferation: involvement of ERK and TGF-β1
DOI: 10.1016/j.jnutbio.2011.08.003
Abstract: This study was conducted to investigate the proliferative effect of vegetable soy peptides on adult stem cells (ASCs) in the absence of serum and their possible mechanisms of action. The pro...
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Jienny Lee,
Kyung-Baeg Roh,
Sang-Cheol Kim,
Jongsung Lee,
Deokhoon Park
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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HuR-mediated posttranscriptional regulation of p21 is involved in the effect of Glycyrrhiza uralensis licorice aqueous extract on polyamine-depleted intestinal crypt cells proliferation
DOI: 10.1016/j.jnutbio.2011.07.009
Abstract: Glycyrrhiza uralensis licorice has long been used worldwide as a food additive and herbal medicine. It possesses a remarkable healing action on gastrointestinal ulcers. The present study was...
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Yi He,
Xian Zhang,
Xing Zeng,
Yu Huang,
Jian-An Wei,
Ling Han,
Cai-Xia Li,
Guo-Wei Zhang
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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Down-regulation of vascular HMGB1 and RAGE expression by n-3 polyunsaturated fatty acids is accompanied by amelioration of chronic vasculopathy of small bowel allografts
DOI: 10.1016/j.jnutbio.2011.08.002
Abstract: Chronic allograft rejection, which is manifested as chronic allograft vasculopathy (CAV), continues to refrain the long-term success of small bowel transplantation (SBTx). The pathway mediat...
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Wei Wei,
Min Chen,
Yanfei Zhu,
Jian Wang,
Ping Zhu,
Yousheng Li,
Jieshou Li
et al.
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Full-length article
(In Press Corrected Proof)
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04 January 2012 |
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Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages
DOI: 10.1016/j.jnutbio.2011.07.007
Abstract: Reverse cholesterol transport (RCT), a process to deliver excess cholesterol from the periphery to the liver for excretion from body, is a major atheroprotective property of high-density lip...
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Chai Siah Ku,
Youngki Park,
Sara L. Coleman,
Jiyoung Lee
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer
DOI: 10.1016/j.jnutbio.2011.07.002
Abstract: Inflammation associated with obesity may play a role in colorectal carcinogenesis, but the underlying mechanism remains unclear. This study investigated whether the Wnt pathway, an intracell...
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Zhenhua Liu,
Ryan S. Brooks,
Eric D. Ciappio,
Susan J. Kim,
Jimmy W. Crott,
Grace Bennett,
Andrew S. Greenberg,
Joel B. Mason
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Abnormal anandamide metabolism in celiac disease
DOI: 10.1016/j.jnutbio.2011.06.017
Abstract: The endocannabinoid system has been extensively investigated in experimental colitis and inflammatory bowel disease, but not in celiac disease, where only a single study showed increased lev...
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Natalia Battista,
Antonio Di Sabatino,
Monia Di Tommaso,
Paolo Biancheri,
Cinzia Rapino,
Francesca Vidali,
Cinzia Papadia,
Chiara Montana,
Alessandra Pasini,
Alberto Lanzini,
Vincenzo Villanacci,
Gino R. Corazza,
Mauro Maccarrone
et al.
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Full-length article
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03 January 2012 |
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Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: molecular evidence of its antioxidant and anti-inflammatory properties
DOI: 10.1016/j.jnutbio.2011.06.018
Abstract: Hepatic ischemia and reperfusion injury (I/R) is accompanied by excessive reactive oxygen species and resultant sterile inflammation. Chlorogenic acid (CGA), one of the most abundant polyphe...
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Nari Yun,
Jung-Woo Kang,
Sun-Mee Lee
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Nitric oxide mediates low magnesium inhibition of osteoblast-like cell proliferation
DOI: 10.1016/j.jnutbio.2011.06.016
Abstract: An adequate intake of magnesium (Mg) is important for bone cell activity and contributes to the prevention of osteoporosis. Because (a) Mg is mitogenic for osteoblasts and (b) reduction of o...
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Marzia Leidi,
Federica Dellera,
Massimo Mariotti,
Giuseppe Banfi,
Calogero Crapanzano,
Walter Albisetti,
Jeanette A.M. Maier
et al.
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Full-length article
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03 January 2012 |
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Comparison of intracellular zinc signals in nonadherent lymphocytes from young-adult and elderly donors: role of zinc transporters (Zip family) and proinflammatory cytokines
DOI: 10.1016/j.jnutbio.2011.07.005
Abstract: Intracellular zinc homeostasis is crucial in regulating the inflammatory/immune response at any age. It is tightly regulated by zinc transporters that control influx, efflux and compartmenta...
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Robertina Giacconi,
Marco Malavolta,
Laura Costarelli,
Franco Busco,
Roberta Galeazzi,
Gianni Bernardini,
Nazzarena Gasparini,
Eugenio Mocchegiani
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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A luciferase reporter assay to investigate the differential selenium-dependent stability of selenoprotein mRNAs
DOI: 10.1016/j.jnutbio.2011.07.010
Abstract: The mechanisms regulating the differential selenium (Se)-dependent stability of selenoprotein mRNAs are partially characterized. To further study the Se-dependent regulation of selenoprotein...
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Shuvojit Banerjee,
Siming Yang,
Charles B. Foster
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice
DOI: 10.1016/j.jnutbio.2011.07.003
Abstract: Aromatase is responsible for the rate-determining reaction in estrogen synthesis and is a prime target for treating estrogen-receptor-positive breast cancer. Previous in vitro study has demo...
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Lan Ye,
Franky L. Chan,
Shiuan Chen,
Lai K. Leung
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP)
DOI: 10.1016/j.jnutbio.2011.06.015
Abstract: Hydrogenation of oils and diary products of ruminant animals leads to an increasing amount of trans fatty acids in the human diet. Trans fatty acids are incorporated in several lipids and ac...
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Marcus O.W. Grimm,
Tatjana L. Rothhaar,
Sven Grösgen,
Verena K. Burg,
Benjamin Hundsdörfer,
Viola J. Haupenthal,
Petra Friess,
Stefan Kins,
Heike S. Grimm,
Tobias Hartmann
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Postweaning low-calcium diet promotes later-life obesity induced by a high-fat diet
DOI: 10.1016/j.jnutbio.2011.07.004
Abstract: The aim of this study was to investigate the effects of a postweaning low-calcium diet on later obesity and explore the underlying mechanisms. Ninety-six male rats were weaned at 3 weeks of ...
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Yong-Han He,
Song-Tao Li,
Yan-Yan Wang,
Guan Wang,
Ying He,
Xi-Lu Liao,
Chang-Hao Sun,
Ying Li
et al.
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Full-length article
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03 January 2012 |