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Editorial Board
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CO2
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Non-resective surgery and radiosurgery for treatment of drug-resistant epilepsy
16 January 2012
Summary: Epilepsy surgery is an effective treatment for properly selected patients with intractable seizures. However, many patients with medically intractable epilepsy are not excellent candidates fo...
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Pantaleo Romanelli,
Pasquale Striano,
Manlio Barbarisi,
Giangennaro Coppola,
David J. Anschel
et al.
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193-201
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Epileptic seizures from abnormal networks: Why some seizures defy predictability
14 December 2011
Summary: Seizure prediction has proven to be difficult in clinically realistic environments. Is it possible that fluctuations in cortical firing could influence the onset of seizures in an ictal zone?...
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William S. Anderson,
Feraz Azhar,
Pawel Kudela,
Gregory K. Bergey,
Piotr J. Franaszczuk
et al.
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202-213
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Ictal MEG onset source localization compared to intracranial EEG and outcome: Improved epilepsy presurgical evaluation in pediatrics
19 December 2011
Summary: Purpose: Magnetoencephalography (MEG) has been shown a useful diagnostic tool for presurgical evaluation of pediatric medically intractable partial epilepsy as MEG source localization has bee...
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Hisako Fujiwara,
Hansel M. Greiner,
Nat Hemasilpin,
Ki Hyeong Lee,
Katherine Holland-Bouley,
Todd Arthur,
Diego Morita,
Sejal V. Jain,
Francesco T. Mangano,
Ton deGrauw,
Douglas F. Rose
et al.
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214-224
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Increases in seizure latencies induced by subcutaneous docosahexaenoic acid are lost at higher doses
30 January 2012
Summary: Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid (PUFA) which has been found to have anticonvulsant properties. Our group has previously reported in a pilot study that the acute adm...
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Marc-Olivier Trépanier,
Ameer Y. Taha,
Rebecca L. Mantha,
Flaviu A. Ciobanu,
Qiudi H. Zeng,
George M. Tchkhartichvili,
Anthony F. Domenichiello,
Richard P. Bazinet,
W.M. Burnham
et al.
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225-232
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Beta adrenergic blockade prevents cardiac dysfunction following status epilepticus in rats
03 January 2012
Summary: Status epilepticus (SE) can result in temporary cardiac dysfunction in patients, characterized by reduced ejection fraction, decreased ventricular contractility, and alterations in electrical...
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Jason G. Little,
Steven L. Bealer
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233-239
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Clusterin interaction with Bcl-xL is associated with seizure-induced neuronal death
26 December 2011
Summary: Status epilepticus causes significant damage to the brain, and cellular injury due to prolonged seizures may cause the pathogenesis of epilepsy or cognitive deficits. Clusterin mediates sever...
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Yoon Sook Kim,
Mee Young Choi,
Ji Ho Ryu,
Dong Hoon Lee,
Byeong Tak Jeon,
Gu Seob Roh,
Sang Soo Kang,
Hyun Joon Kim,
Gyeong Jae Cho,
Wan Sung Choi
et al.
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240-251
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Neuroethologically delineated differences in the seizure behavior of Synapsin 1 and Synapsin 2 knock-out mice
11 January 2012
Summary: The highly homologous nerve terminal phosphoproteins synapsin I and synapsin II have been linked to the pathogenesis of epilepsy through associations between synapsin gene mutations and epile...
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Lars Etholm,
Elma Bahonjic,
Sven Ivar Walaas,
Hung-Teh Kao,
Paul Heggelund
et al.
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252-259
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Serotonin gene polymorphisms and psychiatry comorbidities in temporal lobe epilepsy
05 January 2012
Summary: Objective: Neuropsychiatric comorbidities are frequent in temporal lobe epilepsy (TLE). It is biologically plausible that alterations in serotonin-related genes may be involved in higher susc...
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Laila Cigana Schenkel,
José Augusto Bragatti,
Juliana Allebrand Becker,
Carolina Machado Torres,
Kelin Cristine Martin,
Ana Claudia de Souza,
Gisele Gus Manfro,
Sandra Leistner-Segal,
Marino Muxfeldt Bianchin
et al.
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260-266
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White matter impairment in the basal ganglia-thalamocortical circuit of drug-naïve childhood absence epilepsy
09 January 2012
Summary: Purpose: It is unknown whether white matter abnormalities exist in childhood absence epilepsy (CAE), a syndrome of idiopathic epilepsy (IGE). Diffusion tensor imaging (DTI) can noninvasively ...
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Tianhua Yang,
Zhiwei Guo,
Cheng Luo,
Qifu Li,
Bo Yan,
Ling Liu,
Qiyong Gong,
Dezhong Yao,
Dong Zhou
et al.
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267-273
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Is ictal dystonia associated with an inhibitory effect on seizure propagation in focal epilepsies?
25 January 2012
Summary: Purpose: In focal epilepsy, ictal version and ictal dystonia are thought to reflect seizure spread into the frontal eye field and the basal ganglia, respectively. Here we investigated whether...
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Berend Feddersen,
Jan Remi,
Margret Kilian,
Laurent Vercueil,
Colin Deransart,
Antoine Depaulis,
Soheyl Noachtar
et al.
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274-280
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EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes
12 January 2012
Summary: Objective: We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE pa...
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B. Clemens,
S. Puskás,
M. Besenyei,
M. Emri,
G. Opposits,
S.A. Kis,
K. Hollódy,
A. Fogarasi,
I. Kondákor,
K. Füle,
K. Bense,
I. Fekete
et al.
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281-292
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Hypoxia enhances high-voltage-activated calcium currents in rat primary cortical neurons via calcineurin
16 January 2012
Summary: Hypoxia regulates neuronal ion channels, sometimes resulting in seizures. We evaluated the effects of brief sustained hypoxia (1% O2, 4h) on voltage-gated calcium channels (VGCCs) in cultured...
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Kun Xiang,
Damien Earl,
Trisha Dwyer,
Brian L. Behrle,
Elizabeth I. Tietz,
L. John Greenfield
et al.
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293-305
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Effect of valproic acid treatment on penile structure in prepubertal rats
27 January 2012
Summary: Introduction: The aim of this study was to determine the histological effects of valproic acid (VPA) on the penis in prepubertal rats. Methods: Twelve male Wistar rats (21–24 days old) were d...
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Ömer Kutlu,
Ali Cansu,
Ersagun Karagüzel,
Seren Gülşen Gürgen,
Özgür Koç,
Metin Gür,
Güner Kemal Özgür
et al.
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306-311
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Triheptanoin in acute mouse seizure models
20 January 2012
Abstract: Triheptanoin, the triglyceride of heptanoate, is used to treat certain hereditary metabolic diseases in USA because of its anaplerotic potential. In two chronic mouse seizure models this cle...
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Nicola K. Thomas,
Sarah Willis,
Lawrence Sweetman,
Karin Borges
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312-317
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Prevalence of epilepsy in the 15 years and older in Benin: A door-to-door nationwide survey
27 January 2012
Summary: Purpose: Estimate the prevalence of epilepsy in the 15 years and older in Benin. Methods: We used a random multistage sampling design to select a representative sample of the 15 years and old...
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Luce-Perrine Yemadje,
Dismand Houinato,
Farid Boumédiène,
Edgar Brice Ngoungou,
Pierre-Marie Preux,
Michel Druet-Cabanac
et al.
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318-326
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Cortical and thalamic resting-state functional connectivity is altered in childhood absence epilepsy
27 January 2012
Summary: Purpose: Functional imaging studies have identified a common network of brain regions that activate and deactivate during the generalised spike wave (GSW) discharges of childhood absence epil...
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Richard A. Masterton,
Patrick W. Carney,
Graeme D. Jackson
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327-334
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Occipital lobe epilepsy in children: Characterization, evaluation and surgical outcomes
19 January 2012
Summary: Introduction: Occipital lobe epilepsy (OLE) poses a diagnostic challenge to clinicians. Here, we present our experience in the surgical management of OLE in children using magnetoencephalogra...
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George M. Ibrahim,
Aria Fallah,
Gregory W. Albert,
Teresa Withers,
Hiroshi Otsubo,
Ayako Ochi,
Tomoyuki Akiyama,
Elizabeth J. Donner,
Shelly Weiss,
O. Carter Snead,
James M. Drake,
James T. Rutka
et al.
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335-345
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| Short Communication |
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A de novo balanced t(2;6)(p15;p22.3) in a patient with West Syndrome disrupts a lnc-RNA
16 January 2012
Summary: In a male patient with West Syndrome we identified a perfectly balanced, de novo balanced translocation 46,XY,t(2;6)(p15;p22.3). No known protein coding genes were disrupted by the translocat...
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Geert Vandeweyer,
Nathalie Van der Aa,
Berten Ceulemans,
Bregje W.M. van Bon,
Liesbeth Rooms,
R. Frank Kooy
et al.
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346-349
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