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Variability of sclerosis along the longitudinal hippocampal axis in epilepsy: A post mortem study
18 May 2012
Maria Thom, Ioannis Liagkouras, Lillian Martinian, Joan Liu, Claudia B. Catarino, Sanjay M. Sisodiya
Summary: Detailed neuropathological studies of the extent of hippocampal sclerosis (HS) in epilepsy along the longitudinal axis of the hippocampus are lacking. Neuroimaging studies of patients with te...
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Discontinuation of antiepileptic drugs after successful epilepsy surgery. A Canadian survey
17 May 2012
José F. Téllez-Zenteno, Lizbeth Hernández Ronquillo, Nathalie Jette, Jorge G. Burneo, Dang Khoa Nguyen, Elizabeth J. Donner, Mark Sadler, Mano Javidan M, Donald W. Gross, Samuel Wiebe, Canadian Epilepsy Surgery Study Group
Summary: Introduction: To identify the perceived practice among Canadian epileptologists regarding discontinuation of antiepileptic drugs (AEDs) following successful resective surgery for temporal and...
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Acute encephalopathy with a novel point mutation in the SCN2A gene
16 May 2012
Katsuhiro Kobayashi, Hiroki Ohzono, Mayu Shinohara, Makiko Saitoh, Iori Ohmori, Yoko Ohtsuka, Masashi Mizuguchi
Summary: Mutations of the neuronal voltage-gated sodium channel alpha subunit type II (SCN2A) cause various epileptic syndromes, but have never been reported in association with acute encephalopathy. ...
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Pilocarpine-induced status epilepticus increases Homer1a and changes mGluR5 expression
16 May 2012
C.F. Cavarsan, F. Tescarollo, C. Tesone-Coelho, R.L.T. Morais, F.L.T. Motta, M.M. Blanco, L.E. Mello
Summary: Homer1a regulates expression of group I metabotropic glutamate receptors type I (mGluR1 and mGluR5) and is involved in neuronal plasticity. It has been reported that Homer1a expression is upr...
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Stereotactic radiofrequency amygdalohippocampectomy for the treatment of temporal lobe epilepsy: Do good neuropsychological and seizure outcomes correlate with hippocampal volume reduction?
16 May 2012
Hana Malikova, Lenka Kramska, Roman Liscak, Zdenek Vojtech, Tomas Prochazka, Iva Mareckova, Jiri Lukavsky, Rastislav Druga
Summary: Temporal lobe surgery bears the risk of a decline of neuropsychological functions. Stereotactic radiofrequency amygdalohippocampectomy (SAHE) represents an alternative to mesial temporal lobe...
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