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Changes in brain glucose metabolism in subthalamic nucleus deep brain stimulation for advanced parkinson's disease
16 May 2012
M.A. Volonté, V. Garibotto, F. Spagnolo, A. Panzacchi, P. Picozzi, A. Franzin, E. Giovannini, L. Leocani, M. Cursi, G. Comi, D. Perani
Abstract: Background: Despite its large clinical application, our understanding about the mechanisms of action of deep brain stimulation of the subthalamic nucleus is still limited. Aim of the present...
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Amplitude fluctuations in essential tremor
16 May 2012
Giovanni Mostile, Robert Fekete, Joseph P. Giuffrida, Toby Yaltho, Anthony Davidson, Alessandra Nicoletti, Mario Zappia, Joseph Jankovic
Abstract: Objective: To assess temporal amplitude variability in patients with essential tremor (ET). Methods: Patients who satisfied the diagnostic criteria for probable or definite ET were enrolled ...
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The relationship between cortical and spinal hyperexcitability and clinical disease severity in stiff-man syndrome
14 May 2012
Samuel D. Kim, Steve Vucic, Neil Mahant, Matthew C. Kiernan, Victor S.C. Fung
Stiff-man syndrome (SMS) is an autoimmune disorder characterised by fluctuating muscular rigidity and spasms, most prominent in axial and proximal limb muscles usually in a symmetric manner. Serum ant...
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Epigenetic engineering to reverse the Parkinson’s expression state
14 May 2012
André X.C.N. Valente, Ricardo Pires das Neves, Paulo J. Oliveira
Abstract: Nature, initiation and ensuing cellular propagation mode of sporadic Parkinson’s disease (comprising over 90% of all Parkinson’s cases) remain open research questions. Accordingly, so does t...
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Meta-analysis on MIBG scintigraphy in differential diagnosis between Parkinson's disease and neurodegenerative parkinsonism
10 May 2012
Giorgio Treglia, Ernesto Cason
We read with great interest the recent article written by Orimo et al. and published online .
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